Description:
Nilutamide is a non-steroidal and silent antiandrogen that binds to androgen receptors and also inhibits androgen biosynthesis in vitro. In rats in vivo it inhibits androgen-induced prostate weight increase and inhibits negative androgen-dependent gonadotropin feedback leading to an increase in luteinising hormone and testosterone.
- Molecular Weight:317.224
- Melting Point:153-155 ºC
- Purity:>98%
Molecular Formula:
C12H10F3N3O4
Canonical SMILES:
CC1(C(=O)N(C(=O)N1)C2=CC(=C(C=C2)[N+](=O)[O-])C(F)(F)F)C
InChI:
InChI=1S/C12H10F3N3O4/c1-11(2)9(19)17(10(20)16-11)6-3-4-8(18(21)22)7(5-6)12(13,14)15/h3-5H,1-2H3,(H,16,20)
InChIKey:
XWXYUMMDTVBTOU-UHFFFAOYSA-N
Solubility:
4.19e-03 g/L
Appearance:
Pale Yellow Solid
Application:
Antineoplastic Agents
Synonyms:
Anandron; Nilandron; 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione Más detalles se encuentran
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