Description:
Pevonedistat, also known as MLN-4924 and TAK-924, is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity.
- Molecular Weight:443.52
- Purity:≥98% (HPLC)
Molecular Formula:
C21H25N5O4S
Canonical SMILES:
C1CC2=CC=CC=C2C1NC3=C4C=CN(C4=NC=N3)C5CC(C(C5)O)COS(=O)(=O)N
InChI:
InChI=1S/C21H25N5O4S/c22-31(28,29)30-11-14-9-15(10-19(14)27)26-8-7-17-20(23-12-24-21(17)26)25-18-6-5-13-3-1-2-4-16(13)18/h1-4,7-8,12,14-15,18-19,27H,5-6,9-11H2,(H2,22,28,29)(H,23,24,25)/t14-,15+,18-,19-/m0/s1
InChIKey:
MPUQHZXIXSTTDU-QXGSTGNESA-N
Solubility:
Soluble in DMSO, not soluble in water.
Appearance:
White solid powder
Application:
Enzyme Inhibitors
Storage: Dry, dark and at 0-4°C for short term (days to weeks) or -20°C for long term (months to years).
Synonyms:
TAK-924; TAK 924; TAK924; MLN4924; MLN 4924; BAY-73-4506; BAY 73-4506; BAY73-4506 Weitere Informationen finden Sie
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