BGC > Produktsuche > Teriflunomide | 163451-81-8

Molecular Formula: C12H9F3N2O2
Molecular Weight: 270.2072696
Hazard Symbols: Xn
WGKGermany: 3

Description:
Teriflunomide, the active metabolite of leflunomide, is an immunomodulatory drug inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase. It inhibits rapidly dividing cells, including activated T cells, and tyrosine kinase enzymes.

• Molecular Weight:270.21
• Boiling Point:410.8±45.0°C (Predicted)
• Melting Point:229-232°C
• Purity:>98%

Molecular Formula:
C12H9F3N2O2
Canonical SMILES:
CC(=C(C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F)O
InChI:
InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-
InChIKey:
UTNUDOFZCWSZMS-YFHOEESVSA-N
Solubility:
Soluble in DMSO (Slightly), Methanol (Sparingly)
Appearance:
White to Off-white Solid
Application:
Anti-Inflammatory Agents, Non-Steroidal
Storage: Store at -20°C under inert atmosphere
Synonyms:
Leflunomide Impurity B; A77 1726; A771726; A77-1726; HMR1726; HMR-1726; HMR 1726; N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide; 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide; LEF-M; Leflunomide EP Impurity B; Aubagio; (2Z)-2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide; Femorix

Purity: 98%
Smile code: C/C(O)=C(C#N)/C(NC1=CC=C(C(F)(F)F)C=C1)=O
MDL Number: MFCD00910058
MolFormula: C12H9F3N2O2
MolWeight: 270.2073
Available in stock: 82.356

Smile code:
C/C(O)=C(C#N)/C(NC1=CC=C(C(F)(F)F)C=C1)=O
MDL Number:
MFCD00910058
Purity :
98%
Available in stock:
91.884 g