BGC > Produktsuche > Cabazitaxel | 183133-96-2

Appearance	White or almost white crystalline powder
Identification	FT-IR ,HPLC
Water	3.0%
Melting Point	148 C—158 C
Residue on Ignition	≤ 0.1%
Heavy metals	≤ 20ppm
Residual Solvents
Acetone	≤ 5000ppm
Dichloromethane	≤ 600ppm
n-Hexane	≤ 290ppm
Acetic acid	≤ 5000ppm
Ethyl acetate	≤ 5000ppm
Tetrahydrofuran	≤ 720ppm
Ethanol	≤ 5000ppm
Related Substances
Cabazitaxel	≤ 0.3%
10-DABIII	≤ 0.3%
Any other single impurity	≤ 0.1%
Total impurities	≤ 1.0%
Chromatographic purity(By HPLC)	≥ 99.0%

Molecular Formula: C45H57NO14
Molecular Weight: 835.93238
HS Code: 29329990

Appearance	white powder
Purity	99% min
Application	Signal transduction pathway kinase inhibitor

Description:
Cabazitaxel increases CYP3A enzyme activities in rat hepatocytes. The mean ex-vivo human plasma protein binding of Cabazitaxel is 91.6%.

• Molecular Weight:835.93
• Melting Point:181-184°C
• Purity:>98%

Molecular Formula:
C45H57NO14
Canonical SMILES:
CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC
InChI:
InChI=1S/C45H57NO14/c1-24-28(57-39(51)33(48)32(26-17-13-11-14-18-26)46-40(52)60-41(3,4)5)22-45(53)37(58-38(50)27-19-15-12-16-20-27)35-43(8,36(49)34(55-10)31(24)42(45,6)7)29(54-9)21-30-44(35,23-56-30)59-25(2)47/h11-20,28-30,32-35,37,48,53H,21-23H2,1-10H3,(H,46,52)/t28-,29-,30+,32-,33+,34+,35-,37-,43+,44-,45+/m0/s1
InChIKey:
BMQGVNUXMIRLCK-OAGWZNDDSA-N
Appearance:
White crystalline powder
Synonyms:
XRP6258; XRP-6258; XRP 6258; TXD 258; TXD-258; TXD258; RPR116258A; axoid XRP6258; dimethoxydocetaxel US brand name: Jevtana.