BGC > Produktsuche > Losartan potassium | 124750-99-8

Appearance	WHITE TO OFF-WHITE POWDER.
SOLUBILITY	FREELY SOLUBLE IN WATER,
IR	CONFORM TO WS
WATER(KF)	≤ 0.5%
HEAVY METALS	≤ 10PPM
Individual Impurit	≤ 0.2%
Total Impurity	≤ 0.5%
CYCLOHEXANE	≤ 1000PPM
ISOPROPANOL	≤ 2000PPM
ASSAY (HPLC)	98.5%-101.0%

Molecular Formula: C22H22CIKN6OK
Molecular Weight: 461,01

Description:
Losartan is an angiotensin II receptor antagonist that competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. It promotes vasodilatation and counteracts the effects of aldosterone thus can be used as an antihypertensive.

• Molecular Weight:462.01
• Boiling Point:682 °C
• Melting Point:>259°C (subl.)
• Purity:>98%

Molecular Formula:
C22H23ClKN6O
Canonical SMILES:
CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=N[N-]4)CO)Cl.[K+]
InChI:
InChI=1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
InChIKey:
OXCMYAYHXIHQOA-UHFFFAOYSA-N
Appearance:
White to Off-White Solid
Application:
antihypertensive
Synonyms:
MK 954; MK954; MK-954; Cozaar; Lorzaar; Losaprex; Hyzaar; [2-butyl-5-chloro-3-[[4-[2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol

Purity: 98%
Smile code: [O-]CC1=C(Cl)N=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NNN=N4)C=C2.[K+]
MDL Number: MFCD02092704
MolFormula: C22H22ClKN6O
MolWeight: 461.0010
Available in stock: 1539.008

Smile code:
[O-]CC1=C(Cl)N=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NNN=N4)C=C2.[K+]
MDL Number:
MFCD02092704
Purity :
98%
Available in stock:
1301.006 g