Description:
Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibiting greater than 10000-fold selectivity over DPP-8 and DPP-9. Alogliptin is used for the prevention of type 2 diabetes.
- Molecular Weight:339.39
- Melting Point:127-129°C
- Purity:>98%
Molecular Formula:
C18H21N5O2
Canonical SMILES:
CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCCC(C3)N
InChI:
InChI=1S/C18H21N5O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)11-14-6-3-2-5-13(14)10-19/h2-3,5-6,9,15H,4,7-8,11-12,20H2,1H3/t15-/m1/s1
InChIKey:
ZSBOMTDTBDDKMP-OAHLLOKOSA-N
Solubility:
Sparingly soluble
Appearance:
White to Off-White Solid
Application:
Hypoglycemic agents
Synonyms:
(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitril Weitere Informationen finden Sie
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