BGC > Produktsuche > MTDIA hydrochloride | 1399840-35-7

Description:
MTDIA is a methylthioadenosine phosphorylase (MTAP) inhibitor. MTAP is responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. Transition-state (TS) analogues of MTAP are in development as anticancer drug candidates and MTDIA is one of these TS analogues.

• Molecular Weight:329.85
• Purity:98%

Molecular Formula:
C13H20ClN5OS
Canonical SMILES:
NC(N=CN=C12)=C2NC=C1C[N+]3([H])C[C@@H]([C@H](C3)O)CSC.[Cl-]
InChI:
1S/C13H19N5OS.ClH/c1-20-6-9-4-18(5-10(9)19)3-8-2-15-12-11(8)16-7-17-13(12)14;/h2,7,9-10,15,19H,3-6H2,1H3,(H2,14,16,17);1H/t9-,10+;/m1./s1
InChIKey:
XQKMBJFGNRIATG-UXQCFNEQSA-N
Solubility:
Soluble in DMSO
Appearance:
Solid powder
Application:
anticancer drug candidate
Storage: -20°C Freezer
Synonyms:
(3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium chloride; MTDIA; MTDIA HCl; Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; MT-DADMe-ImmA HCl