BGC > Produktsuche > Ripretinib | 1442472-39-0

Molecular Formula: C24H21BrFN5O2
Molecular Weight: 510.3582432

Description:
Ripretinib is an orally bioavailable KIT/PDGFR inhibitor with antitumor effect. It binds to both wild-type and mutant forms of KIT and PDGFRa at their switch pocket binding site.

• Molecular Weight:510.36

Molecular Formula:
C24H21BrFN5O2
Canonical SMILES:
CCN1C2=CC(=NC=C2C=C(C1=O)C3=CC(=C(C=C3Br)F)NC(=O)NC4=CC=CC=C4)NC
InChI:
InChI=1S/C24H21BrFN5O2/c1-3-31-21-12-22(27-2)28-13-14(21)9-17(23(31)32)16-10-20(19(26)11-18(16)25)30-24(33)29-15-7-5-4-6-8-15/h4-13H,3H2,1-2H3,(H,27,28)(H2,29,30,33)
InChIKey:
CEFJVGZHQAGLHS-UHFFFAOYSA-N
Synonyms:
DCC-2618; 1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea