BGC > Produktsuche > ARN-509 | 956104-40-8

Molecular Formula: C21H15F4N5O2S
Molecular Weight: 477.4347128

EINECS:807-449-9
Molecular formula:C21H15F4N5O2S

Description:
Apalutamide is a potent and competitive androgen receptor (AR) antagonist with potential antineoplastic activity. It binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus.

• Molecular Weight:477.43
• Purity:98%

Molecular Formula:
C21H15F4N5O2S
Canonical SMILES:
CNC(=O)C1=C(C=C(C=C1)N2C(=S)N(C(=O)C23CCC3)C4=CN=C(C(=C4)C(F)(F)F)C#N)F
InChI:
InChI=1S/C21H15F4N5O2S/c1-27-17(31)13-4-3-11(8-15(13)22)30-19(33)29(18(32)20(30)5-2-6-20)12-7-14(21(23,24)25)16(9-26)28-10-12/h3-4,7-8,10H,2,5-6H2,1H3,(H,27,31)
InChIKey:
HJBWBFZLDZWPHF-UHFFFAOYSA-N
Appearance:
White to Off-white Solid Powder
Synonyms:
ARN-509; Apalutamide; ARN 509; JNJ56021927; JNJ-56021927; JNJ 56021927; ARN509; 4-[7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide

Purity: 98%
Smile code: O=C(NC)C1=CC=C(N(C(N(C2=CC(C(F)(F)F)=C(C#N)N=C2)C3=O)=S)C43CCC4)C=C1F
MDL Number: MFCD22380626
MolFormula: C21H15F4N5O2S
MolWeight: 477.4347
Available in stock: 202.125

Smile code:
O=C(NC)C1=CC=C(N(C(N(C2=CC(C(F)(F)F)=C(C#N)N=C2)C3=O)=S)C43CCC4)C=C1F
MDL Number:
MFCD22380626
Purity :
98%
Available in stock:
189.318 g