Description:
Ginsenoside Rf, extracted from the traditional Chinese herb ginseng, is a novel natural anticancer products known for its favorable safety and efficacy profiles. It inhibits Ca2+ channels in mammalian sensory neurons through a mechanism requiring G-proteins, whereas a variety of other ginsenosides were relatively ineffective. It might be useful in itself or as a template for designing additional modulators of neuronal Ca2+ channels. It induces G2/M phase cell cycle arrest and apoptosis in human osteosarcoma MG-63 cells through the mitochondrial pathway.
- Molecular Weight:801.03
- Melting Point:>193 °C
- Purity:>98%
Molecular Formula:
C42H72O14
Canonical SMILES:
CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CC(C4C3(CCC(C4(C)C)O)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)CO)O)O)O)C)O)C)O)C
InChI:
1S/C42H72O14/c1-20(2)10-9-13-42(8,52)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-37-34(32(50)30(48)25(19-44)55-37)56-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28
InChIKey:
UZIOUZHBUYLDHW-XUBRWZAZSA-N
Solubility:
Soluble in DMSO
Appearance:
White powder
Application:
Anti-arthritic agent
Storage: Store at -20 °C
Synonyms:
(3b,6a,12b)-3,12,20-Trihydroxydammar-24-en-6-yl-2-O-(b-D-glucopyranosyl)-b-D-glucopyranoside Weitere Informationen finden Sie
hier