BGC > Produktsuche > Entinostat | 209783-80-2

Molecular Formula: C21H20N4O3
Molecular Weight: 376.4085
Hazard Symbols: Xi,T
UN Number: UN 2811 6.1 / PGIII
WGKGermany: 3
HS Code: 29333990

Description:
Entinostat is a histone deacetylase (HDAC) inhibitor displaying antiproliferative and antineoplastic effects. Entinostat induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), which slows cell growth, differentiation, and tumor development in vivo. Entinostat is potentially used as an antitumor drug in combination with other drugs like adriamycin, PARP inhibitors and Hsp90 inhibitors.

• Molecular Weight:376.416
• Melting Point:154-156°C
• Purity:> 98%

Molecular Formula:
C21H20N4O3
Canonical SMILES:
C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3
InChI:
InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)
InChIKey:
INVTYAOGFAGBOE-UHFFFAOYSA-N
Appearance:
Pale Yellow to Yellow Solid
Application:
Histone Deacetylase Inhibitors
Synonyms:
MS275; MS-275; MS 2275; SNDX275; SNDX-275; SNDX 275; Entinostat; pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate

Purity: 98%
Smile code: O=C(OCC1=CC=CN=C1)NCC2=CC=C(C(NC3=CC=CC=C3N)=O)C=C2
MDL Number: MFCD08272435
MolFormula: C21H20N4O3
MolWeight: 376.4085
Available in stock: 40.395

Smile code:
O=C(OCC1=CC=CN=C1)NCC2=CC=C(C(NC3=CC=CC=C3N)=O)C=C2
MDL Number:
MFCD08272435
Purity :
98%
Available in stock:
48.894 g