BGC > Produktsuche > Pracinostat | 929016-96-6

Molecular Formula: C20H30N4O2
Molecular Weight: 358.4778

Description:
Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein-mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis. This agent may possess improved metabolic, pharmacokinetic and pharmacological properties compared to other HDAC inhibitors.

• Molecular Weight:358.486
• Purity:>98%

Molecular Formula:
C20H30N4O2
Canonical SMILES:
CCCCC1=NC2=C(N1CCN(CC)CC)C=CC(=C2)C=CC(=O)NO
InChI:
InChI=1S/C20H30N4O2/c1-4-7-8-19-21-17-15-16(10-12-20(25)22-26)9-11-18(17)24(19)14-13-23(5-2)6-3/h9-12,15,26H,4-8,13-14H2,1-3H3,(H,22,25)/b12-10+
InChIKey:
JHDKZFFAIZKUCU-ZRDIBKRKSA-N
Appearance:
white solid powder
Synonyms:
SB939; SB 939; SB-939; SC-939; SC 939; SC939; Pracinostat.