BGC > Produktsuche > Lkb1/aak1 dual inhibitor | 1093222-27-5

Molecular Formula: C20H13N5O
Molecular Weight: 339.35012

Description:
LKB1/AAK1 dual inhibitor is an effective inhibitor against multi-kinase especially Pim-1 kinase, which has been newly found to be highly expressed in sorts of isolated human cancer cells. Kd: 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1.

• Molecular Weight:339.35
• Purity:98%

Molecular Formula:
C20H13N5O
Canonical SMILES:
C1=CC(=CN=C1)C(=O)NC2=CNC3=NC=C(C=C23)C4=CC=C(C=C4)C#N
InChI:
InChI=1S/C20H13N5O/c21-9-13-3-5-14(6-4-13)16-8-17-18(12-24-19(17)23-11-16)25-20(26)15-2-1-7-22-10-15/h1-8,10-12H,(H,23,24)(H,25,26)
InChIKey:
JTSLALYXYSRPGW-UHFFFAOYSA-N
Solubility:
10 mM in DMSO
Appearance:
Powder
Storage: -20ºC Freeze
Synonyms:
LKB1/AAK1 dual inhibitor; MDK-2275; MDK 2275; MDK2275; Pim1/AKK1-IN-1; N-[5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-3-pyridinecarboxamide; Pim1 AKK1-IN-1