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Molecular Formula: C19H20N2O6S
Molecular Weight: 404.4369

Description:
Apremilast is an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Apremilast specifically inhibits PDE4 and inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells.

• Molecular Weight:460.50
• Boiling Point:741.3±60.0°C (Predicted)
• Melting Point:154-156 °C
• Purity:>98%

Molecular Formula:
C22H24N2O7S
Canonical SMILES:
CCOC1=C(C=CC(=C1)C(CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC
InChI:
InChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1
InChIKey:
IMOZEMNVLZVGJZ-QGZVFWFLSA-N
Solubility:
Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
Appearance:
Off-White to Pale Yellow Solid
Application:
Anti-inflammatory agents, Non-steroidal; phosphodiesterase inhibitors
Storage: Store at 2-8°C
Synonyms:
(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione; (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; CC 10004; CC10004; CC-10004

Usages	Treatment of arthritis
Applications	Treatment of plaque psoriasis and psoriatic arthritis