Proveedores de CAS
218600-53-4
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Identificación | CAS |
218600-53-4 | Formula |
C32H43NO4 |
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8 Proveedores registrados
Amadis Chemical Company Limited
P.R.China
Más detalles se encuentran aquí
Dayang Chem (Hangzhou) Co.,Ltd.
P.R.China
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C32H43NO4 Molecular Weight: 505.68812
Aea.ltd
P.R.China
Finetech Industry Limited
P.R.China
Más detalles se encuentran aquí
Hangzhou Lingrui Chemical Co., Ltd.
P.R.China
BOC Sciences
USA
Description: Bardoxolone methyl (also known as ´RTA 402´ and ´CDDO-methyl ester´) is an orally-available first-in-class synthetic triterpenoid belonging to the antioxidant inflammation modulator (AIM) class. It is the most potent known inducer of the Nrf2 pathway to enter clinical development and works to suppress both oxidative stress and inflammation. - Molecular Weight:505.70
- Boiling Point:600.8ºC at 760 mmHg
- Purity:≥ 98.0%
Molecular Formula: C32H43NO4 Canonical SMILES: CC1(CCC2(CCC3(C(C2C1)C(=O)C=C4C3(CCC5C4(C=C(C(=O)C5(C)C)C#N)C)C)C)C(=O)OC)C InChI: InChI=1S/C32H43NO4/c1-27(2)11-13-32(26(36)37-8)14-12-31(7)24(20(32)17-27)21(34)15-23-29(5)16-19(18-33)25(35)28(3,4)22(29)9-10-30(23,31)6/h15-16,20,22,24H,9-14,17H2,1-8H3/t20-,22-,24?,29-,30+,31+,32-/m0/s1 InChIKey: WPTTVJLTNAWYAO-FUARBKCBSA-N Solubility: Soluble in DMSO, not in water Appearance: Off-white to yellow powder Application: A Nrf2 activator that inhibits proliferation and induces differentiation and apoptosis in various cancer cells; Antioxidant inflammation modulator (AIM); For the treatment of advanced chronic kidney disease (CKD) in type 2 diabetes mellitus patients Storage: Store in dry, dark and ventilated place. Synonyms: CDDO Methyl ester; CDDOMe; RTA 402; RTA-402; RTA402; TP-155; TP155; TP 155; 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid methyl ester; bardoxolone methyl; CDDO-Me; methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate; (4aS,6aR,6bS,8aR,12aS,14bS)-Methyl 11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicene-4a-carboxylate Más detalles se encuentran aquí
CM Fine Chemicals
Switzerland
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