Description:
RG7800 is a selective Survival of motor neuron 1 protein (SMN1) stimulant and Survival of motor neuron 2 protein (SMN2) modulator originated by Roche. RG7800 shows excellent pharmacokinetic and in vivo efficacy and has a favorable safety profile. RG7800 can correct alternative splicing of the human. Phase I/II clinical trials for the treatment of Spinal muscular atrophyis on-going.
- Molecular Weight:416.52
- Purity:98%
Molecular Formula:
C24H28N6O
Canonical SMILES:
O=C1C=C(C2=NN3C(C(CC)=NC(C)=C3)=C2)N=C4N1C=C(C5CCN(C)CC5)C=C4C
Solubility:
Soluble in DMSO
Appearance:
Powder
Application:
Spinal muscular atrophy
Storage: -20°C Freezer
Synonyms:
RG7800; RG-7800; RG 7800; RO6885247; RO-6885247; RO 6885247. 2-(4-ethyl-6-methylpyrazolo[1,5-a]pyrazin-2-yl)-9-methyl-7-(1-methylpiperidin-4-yl)-4H-pyrido[1,2-a]pyrimidin-4-one Más detalles se encuentran
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