BGC > Buscar Producto > Ro 40-5967 | 116666-63-8

Molecular Formula: C29H40Cl2FN3O3
Molecular Weight: 568.5506032
WGKGermany: 3

Description:
The dihydrochloride hydrate salt form of Mibefradil which is a calcium channel blocker with modest selectivity for T-type Ca2+ channels so that it could be used in the treatment of sorts of cardiovascular disease like hypertension and chronic angina pectoris.

• Molecular Weight:568.55
• Boiling Point:647.6ºC at 760 mmHg
• Purity:95%

Molecular Formula:
C29H40Cl2FN3O3
Canonical SMILES:
CC(C)C1C2=C(CCC1(CCN(C)CCCC3=NC4=CC=CC=C4N3)OC(=O)COC)C=C(C=C2)F.Cl.Cl
InChI:
InChI=1S/C29H38FN3O3.2ClH/c1-20(2)28-23-12-11-22(30)18-21(23)13-14-29(28,36-27(34)19-35-4)15-17-33(3)16-7-10-26-31-24-8-5-6-9-25(24)32-26;;/h5-6,8-9,11-12,18,20,28H,7,10,13-17,19H2,1-4H3,(H,31,32);2*1H/t28-,29-;;/m0../s1
InChIKey:
MTJLQTFHJIHXIX-GDUXWEAWSA-N
Solubility:
Soluble to 100 mM in DMSO, to 50 mM in water.
Appearance:
Solid Powder
Application:
Antihypertensive Agents
Storage: Store at -20ºC
Synonyms:
Mibefradil 2HCl; [(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methoxyacetate dihydrochloride