Description:
9-Aminocamptothecin is a water-insoluble camptothecin derivative and an inhibitor of the nuclear enzyme topoisomerase I, disrupting the repair of single-strand DNA breakages.
- Molecular Weight:363.37
- Boiling Point:819.6±65.0°C (Predicted)
- Melting Point:142.0-145.0°C
- Purity:>98%
Molecular Formula:
C20H17N3O4
Canonical SMILES:
CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC=C5N=C4C3=C2)N)O
InChI:
InChI=1S/C20H17N3O4/c1-2-20(26)13-7-16-17-10(6-11-14(21)4-3-5-15(11)22-17)8-23(16)18(24)12(13)9-27-19(20)25/h3-7,26H,2,8-9,21H2,1H3/t20-/m0/s1
InChIKey:
FUXVKZWTXQUGMW-FQEVSTJZSA-N
Solubility:
Soluble in DMSO.
Appearance:
Powder
Application:
Antineoplastic Agents
Storage: 2-8°C (Protect from light)
Synonyms:
9-amino-camptothecin; 9-amino-CPT; 9-AC; 9-amino-20(S)-camptothecin; 9-amino-20-camptothecin; Aminocamptothecin Weitere Informationen finden Sie
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