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Suppliers for
Efinaconazole
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Properties | CAS |
164650-44-6 | Formula |
C18H22F2N4O |
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11 Registered suppliers
More details are to be found here
API single impurity ≤0.1%,EE ≥99%
Drug Category: ANTI FUNGAL Site: Virupaksha Organics Ltd
Drug Category: ANTI FUNGAL Site: Virupaksha Organics Ltd
Drug Category: ANTI FUNGAL Site: Virupaksha Organics Ltd
Drug Category: ANTI FUNGAL Site: Virupaksha Organics Ltd
Description : Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14α-demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14α-demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following microorganisms, both in vitro and in clinical infections. Efinaconazole exhibits in vitro minimum inhibitory concentrations (MICs) of 0.06 μg/mL or less against most ( ≥ 90%) isolates of the following microorganisms: Trichophyton rubrum; Trichophyton mentagrophytes. - Molecular Weight :348.39
- Purity :> 98%
Molecular Formula : C18H22F2N4O Canonical SMILES : CC(C(CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3CCC(=C)CC3 InChI : InChI=1S/C18H22F2N4O/c1-13-5-7-23(8-6-13)14(2)18(25,10-24-12-21-11-22-24)16-4-3-15(19)9-17(16)20/h3-4,9,11-12,14,25H,1,5-8,10H2,2H3/t14-,18-/m1/s1 InChIKey : NFEZZTICAUWDHU-RDTXWAMCSA-N Synonyms : KP103; KP-103; KP 103; CTK5J2975; AGJ95634; KB145948; AGJ 95634; KB 145948; AGJ-95634; KB-145948; Efinaconazole; trade name: Jublia.
More details are to be found here
Description : Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14α-demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14α-demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following microorganisms, both in vitro and in clinical infections. Efinaconazole exhibits in vitro minimum inhibitory concentrations (MICs) of 0.06 μg/mL or less against most ( ≥ 90%) isolates of the following microorganisms: Trichophyton rubrum; Trichophyton mentagrophytes. - Molecular Weight :348.39
- Purity :> 98%
Molecular Formula : C18H22F2N4O Canonical SMILES : CC(C(CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3CCC(=C)CC3 InChI : InChI=1S/C18H22F2N4O/c1-13-5-7-23(8-6-13)14(2)18(25,10-24-12-21-11-22-24)16-4-3-15(19)9-17(16)20/h3-4,9,11-12,14,25H,1,5-8,10H2,2H3/t14-,18-/m1/s1 InChIKey : NFEZZTICAUWDHU-RDTXWAMCSA-N Synonyms : KP103; KP-103; KP 103; CTK5J2975; AGJ95634; KB145948; AGJ 95634; KB 145948; AGJ-95634; KB-145948; Efinaconazole; trade name: Jublia.
More details are to be found here
Purity : 98% Smile code : C[C@@H](N1CCC(CC1)=C)[C@@](O)(C2=CC=C(F)C=C2F)CN3N=CN=C3 MDL Number : MFCD00936407 MolFormula : C18H22F2N4O MolWeight : 348.3903 Available in stock : 23.614
More details are to be found here
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Properties:
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Last update 2024-05-13
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