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Suppliers for CAS
174022-42-5
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Properties | CAS |
174022-42-5 | Formula |
C36H56O6 |
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3 Registered suppliers
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C36H56O6 Molecular Weight: 584.832
Aea.ltd
P.R.China
Molecular Formula: C36H56O6 Molecular Weight: 584.832
Molecular Formula: C36H56O6 Molecular Weight: 584.832
BOC Sciences
USA
Description : Bevirimat, also known as MPC-4326 and PA-457, is an anti-HIV drug derived from a betulinic acid-like compound, first isolated from Syzygium claviflorum, a Chinese herb. It is believed to inhibit HIV by a novel mechanism, so-called maturation inhibition. Like protease inhibitors, bevirimat and other maturation inhibitors interfere with protease processing of newly translated HIV polyprotein precursor, called gag. Bevirimat prevents this viral replication by specifically inhibiting cleavage of the capsid protein (CA) from the SP1 spacer protein. - Molecular Weight :584.83
- Boiling Point :662.7±40.0 °C at 760 mmHg
- Purity :> 98%
Molecular Formula : C36H56O6 Canonical SMILES : CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)OC(=O)CC(C)(C)C(=O)O)C)C(=O)O InChI : InChI=1S/C36H56O6/c1-21(2)22-12-17-36(30(40)41)19-18-34(8)23(28(22)36)10-11-25-33(7)15-14-26(42-27(37)20-31(3,4)29(38)39)32(5,6)24(33)13-16-35(25,34)9/h22-26,28H,1,10-20H2,2-9H3,(H,38,39)(H,40,41)/t22-,23+,24-,25+,26-,28+,33-,34+,35+,36-/m0/s1 InChIKey : YJEJKUQEXFSVCJ-WRFMNRASSA-N Solubility : In Vitro: DMSO : ≥ 50 mg/mL(85.49 mM) In Vivo: 1.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.5 mg/mL (4.27 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 90% (20%SBE-β-CDin saline) Solubility: 2.5 mg/mL (4.27 mM); Suspended solution; Need ultrasonic and warming 3.Add each solvent one by one:10% DMSO > > 90%corn oil Solubility: ≥ 2.5 mg/mL (4.27 mM); Clear solution Appearance : White to off-white (Solid) Storage : Powder: -20°C 3 years 4°C 2 years In solvent: -80°C 6 months -20°C 1 months Synonyms : MPC4326; MPC 4326; MPC-4326; PA457; PA 457; PA-457; FH11327; FH-11327; FH 11327; YK FH312; Bevirimat; YKFH312
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PA-457
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Last update 2024-04-29
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