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Suppliers for
Toceranib phosphate
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Properties | CAS |
874819-74-6 | Formula |
C22H25FN4O2.H3PO4 |
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6 Registered suppliers
Molecular Formula: C22H28FN4O6P Molecular Weight: 494.4530842
Molecular Formula: C22H28FN4O6P Molecular Weight: 494.4530842
Molecular Formula: C22H28FN4O6P Molecular Weight: 494.4530842
Description : Toceranib phosphate is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFRβ. It is a receptor tyrosine kinase inhibitor and is used in the treatment of canine mast cell tumor also called mastocytoma. It may also have an anti-angiogenic effect. - Molecular Weight :494.45
- Purity :> 98%
Molecular Formula : C22H28FN4O6P Canonical SMILES : CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)C=C3C4=C(C=CC(=C4)F)NC3=O.OP(=O)(O)O InChI : InChI=1S/C22H25FN4O2.H3O4P/c1-13-19(12-17-16-11-15(23)5-6-18(16)26-21(17)28)25-14(2)20(13)22(29)24-7-10-27-8-3-4-9-27;1-5(2,3)4/h5-6,11-12,25H,3-4,7-10H2,1-2H3,(H,24,29)(H,26,28);(H3,1,2,3,4)/b17-12-; InChIKey : AOORBROPMMRREB-HBPAQXCTSA-N Synonyms : SU 11654; PHA 291639; SU11654; SU-11654; PHA-291639; PHA291639
More details are to be found here
Description : Toceranib phosphate is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFRβ. It is a receptor tyrosine kinase inhibitor and is used in the treatment of canine mast cell tumor also called mastocytoma. It may also have an anti-angiogenic effect. - Molecular Weight :494.45
- Purity :> 98%
Molecular Formula : C22H28FN4O6P Canonical SMILES : CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)C=C3C4=C(C=CC(=C4)F)NC3=O.OP(=O)(O)O InChI : InChI=1S/C22H25FN4O2.H3O4P/c1-13-19(12-17-16-11-15(23)5-6-18(16)26-21(17)28)25-14(2)20(13)22(29)24-7-10-27-8-3-4-9-27;1-5(2,3)4/h5-6,11-12,25H,3-4,7-10H2,1-2H3,(H,24,29)(H,26,28);(H3,1,2,3,4)/b17-12-; InChIKey : AOORBROPMMRREB-HBPAQXCTSA-N Synonyms : SU 11654; PHA 291639; SU11654; SU-11654; PHA-291639; PHA291639
More details are to be found here
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Last update 2024-04-29
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