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Molecular Formula: C27H25F3N8O2
Molecular Weight: 551
Hazard Symbols: T
WGKGermany: 3

Molecular Formula: C27H25F3N8O2
Molecular Weight: 551
Hazard Symbols: T
WGKGermany: 3

Molecular Formula: C27H25F3N8O2
Molecular Weight: 551
Hazard Symbols: T
WGKGermany: 3

Description :
SC1 (Pluripotin) was identified in a cell-based chemical library screen for small molecules that regulate mouse embryonic stem (ES) cell self-renewal. SC1 is sufficient to sustain long-term self-renewal of mouse ES cells in an undifferentiated state in the absence of LIF, feeder cells, or serum. SC1 acts through dual inhibition of extracellular signal-regulated kinase 1 (ERK1) and Ras GTPase-activating protein (Ras-GAP). Mouse ES cells maintained in the presence of SC1 retain their ability to differentiate into cells representing all three germ layers in vitro, form chimeric mouse, and contribute to germ line in vivo.

• Molecular Weight :550.54
• Purity :0.98

Molecular Formula :
C27H25F3N8O2
Canonical SMILES :
O=C(NC1=CC=C(C)C(N2CC3=CN=C(NC4=CC(C)=NN4C)N=C3N(C)C2=O)=C1)C5=CC=CC(C(F)(F)F)=C5
Solubility :
Soluble in DMSO, not in water
Appearance :
White solid
Application :
Self-Renewal
Storage : Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Synonyms :
SC-1; SC 1; SC1; Pluripotin

More details are to be found here

Description :
SC1 (Pluripotin) was identified in a cell-based chemical library screen for small molecules that regulate mouse embryonic stem (ES) cell self-renewal. SC1 is sufficient to sustain long-term self-renewal of mouse ES cells in an undifferentiated state in the absence of LIF, feeder cells, or serum. SC1 acts through dual inhibition of extracellular signal-regulated kinase 1 (ERK1) and Ras GTPase-activating protein (Ras-GAP). Mouse ES cells maintained in the presence of SC1 retain their ability to differentiate into cells representing all three germ layers in vitro, form chimeric mouse, and contribute to germ line in vivo.

• Molecular Weight :550.54
• Purity :0.98

Molecular Formula :
C27H25F3N8O2
Canonical SMILES :
O=C(NC1=CC=C(C)C(N2CC3=CN=C(NC4=CC(C)=NN4C)N=C3N(C)C2=O)=C1)C5=CC=CC(C(F)(F)F)=C5
Solubility :
Soluble in DMSO, not in water
Appearance :
White solid
Application :
Self-Renewal
Storage : Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Synonyms :
SC-1; SC 1; SC1; Pluripotin

More details are to be found here

Description :
SC1 (Pluripotin) was identified in a cell-based chemical library screen for small molecules that regulate mouse embryonic stem (ES) cell self-renewal. SC1 is sufficient to sustain long-term self-renewal of mouse ES cells in an undifferentiated state in the absence of LIF, feeder cells, or serum. SC1 acts through dual inhibition of extracellular signal-regulated kinase 1 (ERK1) and Ras GTPase-activating protein (Ras-GAP). Mouse ES cells maintained in the presence of SC1 retain their ability to differentiate into cells representing all three germ layers in vitro, form chimeric mouse, and contribute to germ line in vivo.

• Molecular Weight :550.54
• Purity :0.98

Molecular Formula :
C27H25F3N8O2
Canonical SMILES :
O=C(NC1=CC=C(C)C(N2CC3=CN=C(NC4=CC(C)=NN4C)N=C3N(C)C2=O)=C1)C5=CC=CC(C(F)(F)F)=C5
Solubility :
Soluble in DMSO, not in water
Appearance :
White solid
Application :
Self-Renewal
Storage : Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Synonyms :
SC-1; SC 1; SC1; Pluripotin

More details are to be found here