BGC > Product Search > AT9283 | 896466-04-9

Molecular Formula: C19H23N7O2
Molecular Weight: 381.438

Molecular Formula: C19H23N7O2
Molecular Weight: 381.438

Description :
AT-9283 is a broad spectrum kinase inhibitor that potently inhibits Aurora A, Aurora B, JAK2, JAK3, and c-ABL (IC50= 3, 3, 1.2, 1.1, and 4 nM, respectively). It also potently (IC50 = <1 μM) inhibits serine/threonine kinases as well as receptor and non-receptor tyrosine kinases.

• Molecular Weight :381.43
• Purity :> 98%

Molecular Formula :
C19H23N7O2
Canonical SMILES :
C1CC1NC(=O)NC2=CNNC2=C3N=C4C=CC(=CC4=N3)CN5CCOCC5
InChI :
InChI=1S/C19H23N7O2/c27-19(21-13-2-3-13)24-16-10-20-25-17(16)18-22-14-4-1-12(9-15(14)23-18)11-26-5-7-28-8-6-26/h1,4,9-10,13,20,25H,2-3,5-8,11H2,(H2,21,24,27)/b18-17-
InChIKey :
VRXXZJLHPWWXIX-ZCXUNETKSA-N
Synonyms :
AT9283; AT 9283; AT-9283

More details are to be found here

Description :
AT-9283 is a broad spectrum kinase inhibitor that potently inhibits Aurora A, Aurora B, JAK2, JAK3, and c-ABL (IC50= 3, 3, 1.2, 1.1, and 4 nM, respectively). It also potently (IC50 = <1 μM) inhibits serine/threonine kinases as well as receptor and non-receptor tyrosine kinases.

• Molecular Weight :381.43
• Purity :> 98%

Molecular Formula :
C19H23N7O2
Canonical SMILES :
C1CC1NC(=O)NC2=CNNC2=C3N=C4C=CC(=CC4=N3)CN5CCOCC5
InChI :
InChI=1S/C19H23N7O2/c27-19(21-13-2-3-13)24-16-10-20-25-17(16)18-22-14-4-1-12(9-15(14)23-18)11-26-5-7-28-8-6-26/h1,4,9-10,13,20,25H,2-3,5-8,11H2,(H2,21,24,27)/b18-17-
InChIKey :
VRXXZJLHPWWXIX-ZCXUNETKSA-N
Synonyms :
AT9283; AT 9283; AT-9283

More details are to be found here