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Suppliers for
EGF816
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Properties | CAS |
1508250-71-2 | Formula |
C26H31ClN6O2 |
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4 Registered suppliers
Molecular Formula: C26H31ClN6O2 Molecular Weight: 495.01634
Molecular Formula: C26H31ClN6O2 Molecular Weight: 495.01634
Description : EGF816, also called as Nazartinib, a covalent mutant-selective EGFR inhibitor and potently inhibits the T790M resistance mutation while sparing wild-type EGFR. in vivo: demonstrated strong tumor regressions in several EGFR activating and resistant tumor m Molecular Formula : C26H31ClN6O2 Canonical SMILES : CC1=NC=CC(=C1)C(=O)NC2=NC3=C(N2C4CCCCN(C4)C(=O)C=CCN(C)C)C(=CC=C3)Cl InChI : 1S/C26H31ClN6O2/c1-18-16-19(12-13-28-18)25(35)30-26-29-22-10-6-9-21(27)24(22)33(26)20-8-4-5-15-32(17-20)23(34)11-7-14-31(2)3/h6-7,9-13,16,20H,4-5,8,14-15,17H2,1-3H3,(H,29,30,35)/b11-7+/t20-/m1/s1 InChIKey : IOMMMLWIABWRKL-WUTDNEBXSA-N Solubility : Soluble in DMSO Appearance : Solid powder Storage : Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -45℃ for long term (months to years). Synonyms : EGF816; EGF-816; EGF 816; NVS-816; NVS 816; NVS816; Nazartinib; N-[7-chloro-1-[(3R)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]benzimidazol-2-yl]-2-methylpyridine-4-carboxamideEGF816UNII-KE7K32EME8KE7K32EME8EGF-8161508250-71-2GTPL9204SCHEMBL16767232SCHEMBL16767240EGF 816compound 47 [PMID: 27433829]
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EGF816
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Last update 2024-04-30
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