Suppliers for CAS
1256580-46-7
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Properties | CAS |
1256580-46-7 | Formula |
C30H34N4O2 |
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7 Registered suppliers
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C30H34N4O2 Molecular Weight: 483
Aea.ltd
P.R.China
Molecular Formula: C30H34N4O2 Molecular Weight: 483
Molecular Formula: C30H34N4O2 Molecular Weight: 483
Hangzhou Zhongqi Chem Co., Ltd
P.R.China
Molecular Formula: C30H34N4O2 Molecular Weight: 483
Hangzhou Lingrui Chemical Co., Ltd.
P.R.China
Molecular Formula: C30H34N4O2 Molecular Weight: 483
BOC Sciences
USA
Description : Alectinib, marketed as Alecensa, is an oral drug that blocks the activity of anaplastic lymphoma kinase (ALK) and is used to treat non-small-cell lung cancer (NSCLC). Alectinib has a low potential for interactions. While it is metabolised by the liver enzyme CYP3A4, and blockers of this enzyme accordingly increase its concentrations in the body, they also decrease concentrations of the active metabolite M4, resulting in only a small overall effect. Conversely, CYP3A4 inducers decrease alectinib concentrations and increase M4 concentrations. Interactions via other CYP enzymes and transporter proteins cannot be excluded but are unlikely to be of clinical significance. - Molecular Weight :482.62
- Boiling Point :722.5±60.0 °C at 760 mmHg
- Purity :≥95%
Molecular Formula : C30H34N4O2 Canonical SMILES : CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C InChI : InChI=1S/C30H34N4O2/c1-4-20-16-23-24(17-26(20)34-9-7-21(8-10-34)33-11-13-36-14-12-33)30(2,3)29-27(28(23)35)22-6-5-19(18-31)15-25(22)32-29/h5-6,15-17,21,32H,4,7-14H2,1-3H3 InChIKey : KDGFLJKFZUIJMX-UHFFFAOYSA-N Appearance : White Solid Synonyms : CH-5424802; CH5424802; CH 5424802; AF-802; RG-7853; RO5424802
More details are to be found here
Chemos GmbH & Co. KG
Germany
Description : Alectinib, marketed as Alecensa, is an oral drug that blocks the activity of anaplastic lymphoma kinase (ALK) and is used to treat non-small-cell lung cancer (NSCLC). Alectinib has a low potential for interactions. While it is metabolised by the liver enzyme CYP3A4, and blockers of this enzyme accordingly increase its concentrations in the body, they also decrease concentrations of the active metabolite M4, resulting in only a small overall effect. Conversely, CYP3A4 inducers decrease alectinib concentrations and increase M4 concentrations. Interactions via other CYP enzymes and transporter proteins cannot be excluded but are unlikely to be of clinical significance. - Molecular Weight :482.62
- Boiling Point :722.5±60.0 °C at 760 mmHg
- Purity :≥95%
Molecular Formula : C30H34N4O2 Canonical SMILES : CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C InChI : InChI=1S/C30H34N4O2/c1-4-20-16-23-24(17-26(20)34-9-7-21(8-10-34)33-11-13-36-14-12-33)30(2,3)29-27(28(23)35)22-6-5-19(18-31)15-25(22)32-29/h5-6,15-17,21,32H,4,7-14H2,1-3H3 InChIKey : KDGFLJKFZUIJMX-UHFFFAOYSA-N Appearance : White Solid Synonyms : CH-5424802; CH5424802; CH 5424802; AF-802; RG-7853; RO5424802
More details are to be found here
Santa Cruz Biotechnology, Inc.
USA
Description : Alectinib, marketed as Alecensa, is an oral drug that blocks the activity of anaplastic lymphoma kinase (ALK) and is used to treat non-small-cell lung cancer (NSCLC). Alectinib has a low potential for interactions. While it is metabolised by the liver enzyme CYP3A4, and blockers of this enzyme accordingly increase its concentrations in the body, they also decrease concentrations of the active metabolite M4, resulting in only a small overall effect. Conversely, CYP3A4 inducers decrease alectinib concentrations and increase M4 concentrations. Interactions via other CYP enzymes and transporter proteins cannot be excluded but are unlikely to be of clinical significance. - Molecular Weight :482.62
- Boiling Point :722.5±60.0 °C at 760 mmHg
- Purity :≥95%
Molecular Formula : C30H34N4O2 Canonical SMILES : CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C InChI : InChI=1S/C30H34N4O2/c1-4-20-16-23-24(17-26(20)34-9-7-21(8-10-34)33-11-13-36-14-12-33)30(2,3)29-27(28(23)35)22-6-5-19(18-31)15-25(22)32-29/h5-6,15-17,21,32H,4,7-14H2,1-3H3 InChIKey : KDGFLJKFZUIJMX-UHFFFAOYSA-N Appearance : White Solid Synonyms : CH-5424802; CH5424802; CH 5424802; AF-802; RG-7853; RO5424802
More details are to be found here
Detailed information on the suppliers of
Alectinib
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