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Suppliers for
Pf06650833
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Properties | CAS |
1817626-54-2 |
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3 Registered suppliers
Description : PF-06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), which is an omnipresently expressed serine/threonine kinase involved in the regulation of innate immunity. PF-06650833 is useful for the treatment of autoimmune and inflammatory diseases associated with lnterleukin-1 Receptor Associated Kinase (IRAK) and more particularly modulates the function of IRAK. It is undergoing testing in a Phase II clinical study. - Molecular Weight :361.373
- Boiling Point :621.0±55.0°C at 760mmHg
Molecular Formula : C18H20FN3O4 Canonical SMILES : CCC1C(NC(=O)C1F)COC2=NC=CC3=CC(=C(C=C32)OC)C(=O)N InChI : InChI=1S/C18H20FN3O4/c1-3-10-13(22-17(24)15(10)19)8-26-18-11-7-14(25-2)12(16(20)23)6-9(11)4-5-21-18/h4-7,10,13,15H,3,8H2,1-2H3,(H2,20,23)(H,22,24)/t10-,13+,15-/m0/s1 InChIKey : JKDGKIBAOAFRPJ-ZBINZKHDSA-N Solubility : Soluble in DMSO. Appearance : Solid Powder Storage : Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -42℃ for long term (months to years). Synonyms : zimlovisertib; PF 06650833; PF06650833
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Pf06650833
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Last update 2024-05-07
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