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Suppliers for
Dasatinib
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Properties | CAS |
302962-49-8 | Formula |
C22H26ClN7O2S |
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21 Registered suppliers
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Molecular Formula: C22H28ClN7O3S Molecular Weight: 488.01 HS Code: 29341000
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Molecular Formula: C22H28ClN7O3S Molecular Weight: 488.01 HS Code: 29341000
More details are to be found here
Molecular Formula: C22H28ClN7O3S Molecular Weight: 488.01 HS Code: 29341000
More details are to be found here
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Description : Dasatinib, also known as BMS-354825, is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib binds to and inhibits the growth-promoting activities of these kinases. Apparently because of its less stringent binding affinity for the BCR-ABL kinase, dasatinib has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations. SRC-family protein-tyrosine kinases interact with variety of cell-surface receptors and participate in intracellular signal transduction pathways; tumorigenic forms can occur through altered regulation or expression of the endogenous protein and by way of virally-encoded kinase genes. - Molecular Weight :488.01
- Melting Point :> 250°C (dec.)
- Purity :> 98%
Molecular Formula : C22H26ClN7O2S Canonical SMILES : CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=NC(=NC(=C3)N4CCN(CC4)CCO)C InChI : InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27) InChIKey : ZBNZXTGUTAYRHI-UHFFFAOYSA-N Appearance : White to Off-White Solid Synonyms : BMS-354825; BMS354825; BMS354825
More details are to be found here
Description : Dasatinib, also known as BMS-354825, is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib binds to and inhibits the growth-promoting activities of these kinases. Apparently because of its less stringent binding affinity for the BCR-ABL kinase, dasatinib has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations. SRC-family protein-tyrosine kinases interact with variety of cell-surface receptors and participate in intracellular signal transduction pathways; tumorigenic forms can occur through altered regulation or expression of the endogenous protein and by way of virally-encoded kinase genes. - Molecular Weight :488.01
- Melting Point :> 250°C (dec.)
- Purity :> 98%
Molecular Formula : C22H26ClN7O2S Canonical SMILES : CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=NC(=NC(=C3)N4CCN(CC4)CCO)C InChI : InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27) InChIKey : ZBNZXTGUTAYRHI-UHFFFAOYSA-N Appearance : White to Off-White Solid Synonyms : BMS-354825; BMS354825; BMS354825
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Purity : 98% Smile code : O=C(C1=CN=C(NC2=NC(C)=NC(N3CCN(CCO)CC3)=C2)S1)NC4=C(C)C=CC=C4Cl MDL Number : MFCD11046566 MolFormula : C22H26ClN7O2S MolWeight : 488.0055 Available in stock : 638.664
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Purity : 98% Smile code : O=C(C1=CN=C(NC2=NC(C)=NC(N3CCN(CCO)CC3)=C2)S1)NC4=C(C)C=CC=C4Cl MDL Number : MFCD11046566 MolFormula : C22H26ClN7O2S MolWeight : 488.0055 Available in stock : 638.664
More details are to be found here
Purity : 98% Smile code : O=C(C1=CN=C(NC2=NC(C)=NC(N3CCN(CCO)CC3)=C2)S1)NC4=C(C)C=CC=C4Cl MDL Number : MFCD11046566 MolFormula : C22H26ClN7O2S MolWeight : 488.0055 Available in stock : 638.664
More details are to be found here
Formula: C22H26ClN7O2S Mol Weight: 488,01g/mol
More details are to be found here
Formula: C22H26ClN7O2S Mol Weight: 488,01g/mol
More details are to be found here
Formula: C22H26ClN7O2S Mol Weight: 488,01g/mol
More details are to be found here
Formula: C22H26ClN7O2S Mol Weight: 488,01g/mol
More details are to be found here
Formula: C22H26ClN7O2S Mol Weight: 488,01g/mol
More details are to be found here
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Dasatinib
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Last update 2024-04-30
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