BGC > Product Search > RMC-4550 | 2172651-73-7

Description :
RMC-4550 is a potent and selective SHP-2 inhibitor with IC50 value of 1.55 nM. It inhibits RAS/MAPK signaling in cancer cell lines with Class 3 BRAF mutations.

• Molecular Weight :437.36

Molecular Formula :
C21H26Cl2N4O2
Canonical SMILES :
CC1C(C2(CCN(CC2)C3=NC(=C(N=C3CO)C4=C(C(=CC=C4)Cl)Cl)C)CO1)N
InChI :
InChI=1S/C21H26Cl2N4O2/c1-12-18(14-4-3-5-15(22)17(14)23)26-16(10-28)20(25-12)27-8-6-21(7-9-27)11-29-13(2)19(21)24/h3-5,13,19,28H,6-11,24H2,1-2H3/t13-,19+/m0/s1
InChIKey :
IKUYEYLZXGGCRD-ORAYPTAESA-N
Synonyms :
RMC 4550; RMC4550

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