BGC > Product Search > SC 26196

Description :
SC 26196 is a selective Δ6 desaturase inhibitor (IC50 = 0.2 μM in vitro) that displays > 100 fold selectivity over Δ5 and Δ9 desaturases (IC50 > 200 μM in vitro). SC 26196 completely inhibits the conversion of linoleic acid to arachidonic acid (AA). It exhibits anti-inflammatory properties in a mouse edema model.

• Molecular Weight :423.55
• Purity :≥98% by HPLC

Molecular Formula :
C27H29N5
Canonical SMILES :
C1CN(CCN1CCCC(C#N)(C2=CC=CC=C2)C3=CC=CC=C3)N=CC4=CN=CC=C4
InChI :
InChI=1S/C27H29N5/c28-23-27(25-10-3-1-4-11-25,26-12-5-2-6-13-26)14-8-16-31-17-19-32(20-18-31)30-22-24-9-7-15-29-21-24/h1-7,9-13,15,21-22H,8,14,16-20H2
InChIKey :
QFYKXKMYVYOUNJ-UHFFFAOYSA-N
Synonyms :
α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile; PF-o6341724; FT 0674530; SC 26196; FT0674530; SC26196; FT-0674530; SC-26196

More details are to be found here

Description :
SC 26196 is a selective Δ6 desaturase inhibitor (IC50 = 0.2 μM in vitro) that displays > 100 fold selectivity over Δ5 and Δ9 desaturases (IC50 > 200 μM in vitro). SC 26196 completely inhibits the conversion of linoleic acid to arachidonic acid (AA). It exhibits anti-inflammatory properties in a mouse edema model.

• Molecular Weight :423.55
• Purity :≥98% by HPLC

Molecular Formula :
C27H29N5
Canonical SMILES :
C1CN(CCN1CCCC(C#N)(C2=CC=CC=C2)C3=CC=CC=C3)N=CC4=CN=CC=C4
InChI :
InChI=1S/C27H29N5/c28-23-27(25-10-3-1-4-11-25,26-12-5-2-6-13-26)14-8-16-31-17-19-32(20-18-31)30-22-24-9-7-15-29-21-24/h1-7,9-13,15,21-22H,8,14,16-20H2
InChIKey :
QFYKXKMYVYOUNJ-UHFFFAOYSA-N
Synonyms :
α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile; PF-o6341724; FT 0674530; SC 26196; FT0674530; SC26196; FT-0674530; SC-26196

More details are to be found here

Description :
SC 26196 is a selective Δ6 desaturase inhibitor (IC50 = 0.2 μM in vitro) that displays > 100 fold selectivity over Δ5 and Δ9 desaturases (IC50 > 200 μM in vitro). SC 26196 completely inhibits the conversion of linoleic acid to arachidonic acid (AA). It exhibits anti-inflammatory properties in a mouse edema model.

• Molecular Weight :423.55
• Purity :≥98% by HPLC

Molecular Formula :
C27H29N5
Canonical SMILES :
C1CN(CCN1CCCC(C#N)(C2=CC=CC=C2)C3=CC=CC=C3)N=CC4=CN=CC=C4
InChI :
InChI=1S/C27H29N5/c28-23-27(25-10-3-1-4-11-25,26-12-5-2-6-13-26)14-8-16-31-17-19-32(20-18-31)30-22-24-9-7-15-29-21-24/h1-7,9-13,15,21-22H,8,14,16-20H2
InChIKey :
QFYKXKMYVYOUNJ-UHFFFAOYSA-N
Synonyms :
α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile; PF-o6341724; FT 0674530; SC 26196; FT0674530; SC26196; FT-0674530; SC-26196

More details are to be found here