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Suppliers for CAS
119413-54-6
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Properties | | CAS |
119413-54-6 | | Formula |
C23H23N3O5.HCl |
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15 Registered suppliers
Dayang Chem (Hangzhou) Co.,Ltd.
P.R.China
Xingrui Industry Co., Limited
P.R.China
Hangzhou Meite Industry Co., Ltd (Hangzhou Meite Chemical Co., Ltd)
P.R.China
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C23H23N3O5.HCl;C23H24ClN3O5 Molecular Weight: 457,91
More details are to be found here
Hangzhou Verychem Science & Technology Co., Ltd.
P.R.China
Molecular Formula: C23H23N3O5.HCl;C23H24ClN3O5 Molecular Weight: 457,91
More details are to be found here
Hangzhou Zhongqi Chem Co., Ltd
P.R.China
Molecular Formula: C23H23N3O5.HCl;C23H24ClN3O5 Molecular Weight: 457,91
More details are to be found here
BOC Sciences
USA
Description : Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. - Molecular Weight :457.91
- Melting Point :215°C (dec.)
- Purity :> 98%
Molecular Formula : C23H24ClN3O5 Canonical SMILES : CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O.Cl
InChI :
InChI=1S/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1
InChIKey :
DGHHQBMTXTWTJV-BQAIUKQQSA-N
Solubility :
Soluble in DMSO (Slightly, Sonicated), Methanol (Slightly, Heated), Water (Slightly, Heated)
Appearance :
Light Yellow to Dark Green Solid
Application :
Topoisomerase I Inhibitors
Storage : Store at 2-8°C
Synonyms :
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, hydrochloride (1:1), (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (S)-; (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[l,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride; Hycamtin; Nogitecan hydrochloride; NSC 609669; SKF 104864A; SKFS 104864A; Topotecan chlorohydrate; Xinze
More details are to be found here
Shandong SanYoung Industry Co., Ltd
P.R.China
Description : Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. - Molecular Weight :457.91
- Melting Point :215°C (dec.)
- Purity :> 98%
Molecular Formula : C23H24ClN3O5 Canonical SMILES : CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O.Cl
InChI :
InChI=1S/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1
InChIKey :
DGHHQBMTXTWTJV-BQAIUKQQSA-N
Solubility :
Soluble in DMSO (Slightly, Sonicated), Methanol (Slightly, Heated), Water (Slightly, Heated)
Appearance :
Light Yellow to Dark Green Solid
Application :
Topoisomerase I Inhibitors
Storage : Store at 2-8°C
Synonyms :
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, hydrochloride (1:1), (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (S)-; (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[l,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride; Hycamtin; Nogitecan hydrochloride; NSC 609669; SKF 104864A; SKFS 104864A; Topotecan chlorohydrate; Xinze
More details are to be found here
Ambeed, Inc.
USA
Purity : 98% Smile code : O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.[H]Cl
MDL Number : MFCD00866235
MolFormula : C23H24ClN3O5
MolWeight : 457.9068
Available in stock : 67.808
More details are to be found here
BLD Pharmatech Ltd
P.R.China
Smile code: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.[H]Cl
MDL Number:
MFCD00866235
Purity :
98%
Available in stock:
32.608 g
More details are to be found here
AK Scientific, Inc.
USA
Smile code: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.[H]Cl
MDL Number:
MFCD00866235
Purity :
98%
Available in stock:
32.608 g
More details are to be found here
Chemos GmbH & Co. KG
Germany
Smile code: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.[H]Cl
MDL Number:
MFCD00866235
Purity :
98%
Available in stock:
32.608 g
More details are to be found here
BuGuCh & Partners
Germany
Smile code: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.[H]Cl
MDL Number:
MFCD00866235
Purity :
98%
Available in stock:
32.608 g
More details are to be found here
Evonik ( formerly Wilshire Technologies, Inc. )
USA
Smile code: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.[H]Cl
MDL Number:
MFCD00866235
Purity :
98%
Available in stock:
32.608 g
More details are to be found here
Santa Cruz Biotechnology, Inc.
USA
Smile code: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.[H]Cl
MDL Number:
MFCD00866235
Purity :
98%
Available in stock:
32.608 g
More details are to be found here
Smile code: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.[H]Cl
MDL Number:
MFCD00866235
Purity :
98%
Available in stock:
32.608 g
More details are to be found here
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