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Suppliers for

Entacapone



Properties

CAS   130929-57-6 
Formula   C14H15N3O5 

Structure

18 Registered suppliers


Appearance   yellow white powder
Identification   Should comply with the IR spectrum Exhibits maximum absorption at 354nm
Clarity of solution   5.0% w/v solution in DMF is clear
Related Substances (Impurity A)   ≤ 0.10%
Related Substances (Impurity B)   ≤ 0.10%
Related Substances (Impurity C)   ≤ 0.05%
Related Substances (Impurity D)   ≤ 0.05%
Related Substances (Any other impurity)   ≤ 0.10%
Related Substances (Total Impurities)   ≤ 0.3%
Heavy metals   ≤ 20ppm
Loss on drying   ≤ 0.5%
Sulphated ash   ≤ 0.1%
Assay,on anhydrous basis   99.0%~101.0%
Residual Solvents(Ethanol)   ≤ 5000ppm
Residual Solvents(1,2-Xylene)   ≤ 2170ppm


Appearance   yellow white powder
Identification   Should comply with the IR spectrum Exhibits maximum absorption at 354nm
Clarity of solution   5.0% w/v solution in DMF is clear
Related Substances (Impurity A)   ≤ 0.10%
Related Substances (Impurity B)   ≤ 0.10%
Related Substances (Impurity C)   ≤ 0.05%
Related Substances (Impurity D)   ≤ 0.05%
Related Substances (Any other impurity)   ≤ 0.10%
Related Substances (Total Impurities)   ≤ 0.3%
Heavy metals   ≤ 20ppm
Loss on drying   ≤ 0.5%
Sulphated ash   ≤ 0.1%
Assay,on anhydrous basis   99.0%~101.0%
Residual Solvents(Ethanol)   ≤ 5000ppm
Residual Solvents(1,2-Xylene)   ≤ 2170ppm


Appearance   yellow white powder
Identification   Should comply with the IR spectrum Exhibits maximum absorption at 354nm
Clarity of solution   5.0% w/v solution in DMF is clear
Related Substances (Impurity A)   ≤ 0.10%
Related Substances (Impurity B)   ≤ 0.10%
Related Substances (Impurity C)   ≤ 0.05%
Related Substances (Impurity D)   ≤ 0.05%
Related Substances (Any other impurity)   ≤ 0.10%
Related Substances (Total Impurities)   ≤ 0.3%
Heavy metals   ≤ 20ppm
Loss on drying   ≤ 0.5%
Sulphated ash   ≤ 0.1%
Assay,on anhydrous basis   99.0%~101.0%
Residual Solvents(Ethanol)   ≤ 5000ppm
Residual Solvents(1,2-Xylene)   ≤ 2170ppm


Molecular Formula: C14H15N3O5
Molecular Weight: 305,29

More details are to be found here
Molecular Formula: C14H15N3O5
Molecular Weight: 305,29

More details are to be found here
Molecular Formula: C14H15N3O5
Molecular Weight: 305,29

More details are to be found here
Molecular Formula: C14H15N3O5
Molecular Weight: 305,29

More details are to be found here
Molecular Formula: C14H15N3O5
Molecular Weight: 305,29

More details are to be found here
Description :
Entacapone is a selective and reversible inhibitor of the enzyme catechol-O-methyltransferase (COMT) (IC50 = 151 nM), commonly used in combination with other medications for the treatment of Parkinson's disease.
  • Molecular Weight :305.29
  • Boiling Point :526.6±50.0°C at 760 mmHg
  • Melting Point :162-163°C
  • Purity :> 98%
Molecular Formula :
C14H15N3O5
Canonical SMILES :
CCN(CC)C(=O)C(=CC1=CC(=C(C(=C1)O)O)[N+](=O)[O-])C#N
InChI :
InChI=1S/C14H15N3O5/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9/h5-7,18-19H,3-4H2,1-2H3/b10-5+
InChIKey :
JRURYQJSLYLRLN-BJMVGYQFSA-N
Solubility :
Soluble in Chloroform (Slightly, Heated, Sonicated), Methanol (Slightly)
Appearance :
Yellow Solid
Storage : Store at -20°C
Synonyms :
2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (2E)-; Comtan; HSDB 8251; HSDB-8251; HSDB8251; OR-611; OR 611; OR611; (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide; 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (E)-; (E)-Entacapone; Comtess; Entacom; Parkicapone

More details are to be found here
Purity : 95%
Smile code : O=C(N(CC)CC)/C(C#N)=C/C1=CC([N+]([O-])=O)=C(O)C(O)=C1
MDL Number : MFCD00866580
MolFormula : C14H15N3O5
MolWeight : 305.2860
Available in stock : 179.878

More details are to be found here
Purity : 95%
Smile code : O=C(N(CC)CC)/C(C#N)=C/C1=CC([N+]([O-])=O)=C(O)C(O)=C1
MDL Number : MFCD00866580
MolFormula : C14H15N3O5
MolWeight : 305.2860
Available in stock : 179.878

More details are to be found here
Purity : 95%
Smile code : O=C(N(CC)CC)/C(C#N)=C/C1=CC([N+]([O-])=O)=C(O)C(O)=C1
MDL Number : MFCD00866580
MolFormula : C14H15N3O5
MolWeight : 305.2860
Available in stock : 179.878

More details are to be found here
Purity : 95%
Smile code : O=C(N(CC)CC)/C(C#N)=C/C1=CC([N+]([O-])=O)=C(O)C(O)=C1
MDL Number : MFCD00866580
MolFormula : C14H15N3O5
MolWeight : 305.2860
Available in stock : 179.878

More details are to be found here
Purity : 95%
Smile code : O=C(N(CC)CC)/C(C#N)=C/C1=CC([N+]([O-])=O)=C(O)C(O)=C1
MDL Number : MFCD00866580
MolFormula : C14H15N3O5
MolWeight : 305.2860
Available in stock : 179.878

More details are to be found here

Detailed information on the suppliers of Entacapone

Properties:

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