BGC > Product Search > Pacritinib | 937272-79-2

Molecular Formula: C28H32N4O3
Molecular Weight: 472.59

Molecular Formula: C28H32N4O3
Molecular Weight: 472.59

Molecular Formula: C28H32N4O3
Molecular Weight: 472.59

Description :
Pacritinib is an orally bioavailable and ATP-competitive inhibitor of JAK2 (IC50 = 23 nM), and also inhibits FLT3 (IC50 = 22 nM). It suppresses proliferation in cells carrying the JAK2V617F mutation.

• Molecular Weight :472.589
• Boiling Point :711.4±70.0 °C at 760 mmHg
• Purity :> 98%

Molecular Formula :
C28H32N4O3
Canonical SMILES :
C1CCN(C1)CCOC2=C3COCC=CCOCC4=CC=CC(=C4)C5=NC(=NC=C5)NC(=C3)C=C2
InChI :
InChI=1S/C28H32N4O3/c1-2-13-32(12-1)14-17-35-27-9-8-25-19-24(27)21-34-16-4-3-15-33-20-22-6-5-7-23(18-22)26-10-11-29-28(30-25)31-26/h3-11,18-19H,1-2,12-17,20-21H2,(H,29,30,31)/b4-3+
InChIKey :
HWXVIOGONBBTBY-ONEGZZNKSA-N
Application :
For research used only
Synonyms :
SB1518; SB-1518

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