BGC > Product Search > D-2-Hydroxypentanedioic acid disodium salt | 103404-90-6

Molecular Formula: C5H6Na2O5
Molecular Weight: 192.08
WGKGermany: 3
HS Code: 29181990

Molecular Formula: C5H6Na2O5
Molecular Weight: 192.08
WGKGermany: 3
HS Code: 29181990

Description :
Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM. In U-87MG cells, (R)-2-Hydroxyglutarate acts as a weak antagonist of α-KG to inhibit α-KG-dependent histone demethylases and increase dimethylation on both H3K9 and H3K79.

• Molecular Weight :192.08
• Purity :98%

Molecular Formula :
C5H6Na2O5
Canonical SMILES :
C(CC(=O)[O-])C(C(=O)[O-])O.[Na+].[Na+]
InChI :
InChI=1S/C5H8O5.2Na/c6-3(5(9)10)1-2-4(7)8;;/h3,6H,1-2H2,(H,7,8)(H,9,10);;/q;2*+1/p-2/t3-;;/m1../s1
InChIKey :
DZHFTEDSQFPDPP-HWYNEVGZSA-L
Solubility :
Soluble to 38mg/mL in warmed water; Soluble to < 1mg/mL in DMSO; Soluble to < 1mg/mL in ethanol
Appearance :
Pale Orange Solid
Storage : 3 years -20℃ powder; 6 months -80℃ in solvent
Synonyms :
MDK4906; MDK 4906; MDK-4906; d-α-hydroxyglutaric acid disodium salt; (2R)-2-Hydroxyglutaric Acid Disodium Salt; D-alpha-Hydroxyglutaric acid (disodium salt)

More details are to be found here

Description :
Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM. In U-87MG cells, (R)-2-Hydroxyglutarate acts as a weak antagonist of α-KG to inhibit α-KG-dependent histone demethylases and increase dimethylation on both H3K9 and H3K79.

• Molecular Weight :192.08
• Purity :98%

Molecular Formula :
C5H6Na2O5
Canonical SMILES :
C(CC(=O)[O-])C(C(=O)[O-])O.[Na+].[Na+]
InChI :
InChI=1S/C5H8O5.2Na/c6-3(5(9)10)1-2-4(7)8;;/h3,6H,1-2H2,(H,7,8)(H,9,10);;/q;2*+1/p-2/t3-;;/m1../s1
InChIKey :
DZHFTEDSQFPDPP-HWYNEVGZSA-L
Solubility :
Soluble to 38mg/mL in warmed water; Soluble to < 1mg/mL in DMSO; Soluble to < 1mg/mL in ethanol
Appearance :
Pale Orange Solid
Storage : 3 years -20℃ powder; 6 months -80℃ in solvent
Synonyms :
MDK4906; MDK 4906; MDK-4906; d-α-hydroxyglutaric acid disodium salt; (2R)-2-Hydroxyglutaric Acid Disodium Salt; D-alpha-Hydroxyglutaric acid (disodium salt)

More details are to be found here

Description :
Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM. In U-87MG cells, (R)-2-Hydroxyglutarate acts as a weak antagonist of α-KG to inhibit α-KG-dependent histone demethylases and increase dimethylation on both H3K9 and H3K79.

• Molecular Weight :192.08
• Purity :98%

Molecular Formula :
C5H6Na2O5
Canonical SMILES :
C(CC(=O)[O-])C(C(=O)[O-])O.[Na+].[Na+]
InChI :
InChI=1S/C5H8O5.2Na/c6-3(5(9)10)1-2-4(7)8;;/h3,6H,1-2H2,(H,7,8)(H,9,10);;/q;2*+1/p-2/t3-;;/m1../s1
InChIKey :
DZHFTEDSQFPDPP-HWYNEVGZSA-L
Solubility :
Soluble to 38mg/mL in warmed water; Soluble to < 1mg/mL in DMSO; Soluble to < 1mg/mL in ethanol
Appearance :
Pale Orange Solid
Storage : 3 years -20℃ powder; 6 months -80℃ in solvent
Synonyms :
MDK4906; MDK 4906; MDK-4906; d-α-hydroxyglutaric acid disodium salt; (2R)-2-Hydroxyglutaric Acid Disodium Salt; D-alpha-Hydroxyglutaric acid (disodium salt)

More details are to be found here

Description :
Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM. In U-87MG cells, (R)-2-Hydroxyglutarate acts as a weak antagonist of α-KG to inhibit α-KG-dependent histone demethylases and increase dimethylation on both H3K9 and H3K79.

• Molecular Weight :192.08
• Purity :98%

Molecular Formula :
C5H6Na2O5
Canonical SMILES :
C(CC(=O)[O-])C(C(=O)[O-])O.[Na+].[Na+]
InChI :
InChI=1S/C5H8O5.2Na/c6-3(5(9)10)1-2-4(7)8;;/h3,6H,1-2H2,(H,7,8)(H,9,10);;/q;2*+1/p-2/t3-;;/m1../s1
InChIKey :
DZHFTEDSQFPDPP-HWYNEVGZSA-L
Solubility :
Soluble to 38mg/mL in warmed water; Soluble to < 1mg/mL in DMSO; Soluble to < 1mg/mL in ethanol
Appearance :
Pale Orange Solid
Storage : 3 years -20℃ powder; 6 months -80℃ in solvent
Synonyms :
MDK4906; MDK 4906; MDK-4906; d-α-hydroxyglutaric acid disodium salt; (2R)-2-Hydroxyglutaric Acid Disodium Salt; D-alpha-Hydroxyglutaric acid (disodium salt)

More details are to be found here