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Suppliers for CAS
1201438-56-3
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Properties | | CAS |
1201438-56-3 | | Formula |
C22H17ClN6O |
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5 Registered suppliers
Amadis Chemical Company Limited
P.R.China
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C22H16ClN6O
Molecular Weight: 415.85504
Aea.ltd
P.R.China
Molecular Formula: C22H16ClN6O
Molecular Weight: 415.85504
Molecular Formula: C22H16ClN6O
Molecular Weight: 415.85504
Molecular Formula: C22H16ClN6O
Molecular Weight: 415.85504
BOC Sciences
USA
Description : Duvelisib, also known as IPI-145 and INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities. Upon administration, PI3K delta/gamma inhibitor IPI 145 prevents the activation of the PI3K delta/gamma-mediated signaling pathways which may lead to a reduction in cellular proliferation in PI3K delta/gamma-expressing tumor cells. Unlike other isoforms of PI3K, the delta and gamma isoforms are overexpressed primarily in hematologic malignancies and inflammatory and autoimmune diseases. By selectively targeting these PI3K isoforms, PI3K signaling in normal, non-neoplastic cells is minimally or not affected which would result in a more favorable side effect profile. - Molecular Weight :416.869
Molecular Formula : C22H17ClN6O Canonical SMILES : CC(C1=CC2=C(C(=CC=C2)Cl)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
InChI :
InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26,27,28)/t13-/m0/s1
InChIKey :
SJVQHLPISAIATJ-ZDUSSCGKSA-N
Appearance :
white solid powder
Application :
For research used only
Synonyms :
IPI145; IPI 145; IPI-145. INK-1197; INK 1197; INK1197; Duvelisib.
More details are to be found here
Chemtour Biotech Co., Ltd
P.R.China
Description : Duvelisib, also known as IPI-145 and INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities. Upon administration, PI3K delta/gamma inhibitor IPI 145 prevents the activation of the PI3K delta/gamma-mediated signaling pathways which may lead to a reduction in cellular proliferation in PI3K delta/gamma-expressing tumor cells. Unlike other isoforms of PI3K, the delta and gamma isoforms are overexpressed primarily in hematologic malignancies and inflammatory and autoimmune diseases. By selectively targeting these PI3K isoforms, PI3K signaling in normal, non-neoplastic cells is minimally or not affected which would result in a more favorable side effect profile. - Molecular Weight :416.869
Molecular Formula : C22H17ClN6O Canonical SMILES : CC(C1=CC2=C(C(=CC=C2)Cl)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
InChI :
InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26,27,28)/t13-/m0/s1
InChIKey :
SJVQHLPISAIATJ-ZDUSSCGKSA-N
Appearance :
white solid powder
Application :
For research used only
Synonyms :
IPI145; IPI 145; IPI-145. INK-1197; INK 1197; INK1197; Duvelisib.
More details are to be found here
Detailed information on the suppliers of
Duvelisib |
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