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Suppliers for
Valbenazine
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Properties | CAS |
1025504-45-3 | Formula |
C24H38N2O4 |
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3 Registered suppliers
Molecular Formula: C24H38N2O4 Molecular Weight: 418.56952
Molecular Formula: C24H38N2O4 Molecular Weight: 418.56952
Description : Valbenazine is a potent and highly selective vesicular monoamine transporter 2(VMAT2) inhibitor. It is a prodrug of the (+)-α isomer of tetrabenazine for tardive syndrome therapy. It is effective in regulating the levels of dopamine release during nerve communication, while at the same time having minimal impact on the other monoamines. It significantly improved tardive dyskinesia and was well tolerated in patients. It is an experimental drug being investigated for use in the treatment of tardive dyskinesia and Tourette syndrome. It was developed by Neurocrine Biosciences. - Molecular Weight :418.57
- Boiling Point :507.2±50.0 °C (Predicted)
- Melting Point :> 75°C (dec.)
- Purity :> 98%
Molecular Formula : C24H38N2O4 Canonical SMILES : CC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1OC(=O)C(C(C)C)N)OC)OC InChI : InChI=1S/C24H38N2O4/c1-14(2)9-17-13-26-8-7-16-10-21(28-5)22(29-6)11-18(16)19(26)12-20(17)30-24(27)23(25)15(3)4/h10-11,14-15,17,19-20,23H,7-9,12-13,25H2,1-6H3/t17-,19-,20-,23+/m1/s1 InChIKey : GEJDGVNQKABXKG-CFKGEZKQSA-N Solubility : Soluble in Chloroform (Slightly), Methanol (Slightly) Appearance : Light Yellow to Yellow Solid Application : Valbenazine is an experimental drug being investigated for use in the treatment of tardive dyskinesia and Tourette syndrome. Storage : Store at -20°C under inert atmosphere Synonyms : Ingrezza; L-Valine, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo(a)quinolizin-2-yl ester; (S)-2-amino-3-methyl-butyric acid (2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl ester; Tetrabenazine Related Impurity 28 (2R, 3R, 11bR, L-Val); [(2R,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl] (2S)-2-amino-3-methylbutanoate; NBI-98854; NBI98854; MT-5199; MT5199; NBI 98854; MT 5199
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Properties:
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Last update 2024-04-26
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