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BGC > Product Search > Veliparib | 912444-00-9
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Suppliers for CAS

912444-00-9


Properties

CAS   912444-00-9 
Formula   C13H16N4

Structure

7 Registered suppliers


Amadis Chemical Company Limited P.R.China
Capot Chemical Co., Ltd. P.R.China
Leap Chem Co., Ltd P.R.China
Aea.ltd P.R.China
Molecular Formula: C13H16N4O.2ClH
Molecular Weight: 317.218
Molecular Formula: C13H16N4O.2ClH
Molecular Weight: 317.218
Finetech Industry Limited P.R.China
BOC Sciences USA
Chemos GmbH & Co. KG Germany
Description :
Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively. In HCT-116 and HT-29 cell lines, the ability of ABT-888 to synergize the effect of the anti-cancer agents, SN38 or oxaliplatin, was determined using the SRB assay. PARP activity was significantly reduced in samples treated with SN38 in combination with ABT-888 (> 4 fold at 24 h).
  • Molecular Weight :244.298
  • Purity :0.99
Molecular Formula :
C13H16N4O
Canonical SMILES :
O=C(C1=C2C(NC([C@]3(C)NCCC3)=N2)=CC=C1)N
InChI :
1S/C13H16N4O/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17)/t13-/m1/s1
InChIKey :
JNAHVYVRKWKWKQ-CYBMUJFWSA-N
Appearance :
White to off-white solid powder
Application :
For research used only
Synonyms :
(R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide; ABT888; ABT-888; ABT 888; Veliparib
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Detailed information on the suppliers of Veliparib

Properties:

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