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Suppliers for
Ivacaftor
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Properties | CAS |
873054-44-5 | Formula |
C24H28N2O3 |
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5 Registered suppliers
Description : Ivacaftor is a potentiator of CFTR targeting G551D-CFTR(EC50=100 nM)and F508del-CFTR(EC50=25 nM). Ivacaftor is used in the treatment of cystic fibrosis. - Molecular Weight :392.49
- Boiling Point :550.4±50.0 °C(Predicted)
- Melting Point :212-215°C
- Purity :98%
Molecular Formula : C24H28N2O3 Canonical SMILES : CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C InChI : InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29) InChIKey : PURKAOJPTOLRMP-UHFFFAOYSA-N Solubility : solube in DMSO, Ethyl Acetate, Methanol Appearance : White to Light Brown Solid Application : Chloride Channel Agonists Storage : Store at -20°C Synonyms : N-[2,4-Bis[1,1-di(methyl)ethyl]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; Ivacaftor; Kalydeco; VX-770; VX 770; VX770
More details are to be found here
Description : Ivacaftor is a potentiator of CFTR targeting G551D-CFTR(EC50=100 nM)and F508del-CFTR(EC50=25 nM). Ivacaftor is used in the treatment of cystic fibrosis. - Molecular Weight :392.49
- Boiling Point :550.4±50.0 °C(Predicted)
- Melting Point :212-215°C
- Purity :98%
Molecular Formula : C24H28N2O3 Canonical SMILES : CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C InChI : InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29) InChIKey : PURKAOJPTOLRMP-UHFFFAOYSA-N Solubility : solube in DMSO, Ethyl Acetate, Methanol Appearance : White to Light Brown Solid Application : Chloride Channel Agonists Storage : Store at -20°C Synonyms : N-[2,4-Bis[1,1-di(methyl)ethyl]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; Ivacaftor; Kalydeco; VX-770; VX 770; VX770
More details are to be found here
Description : Ivacaftor is a potentiator of CFTR targeting G551D-CFTR(EC50=100 nM)and F508del-CFTR(EC50=25 nM). Ivacaftor is used in the treatment of cystic fibrosis. - Molecular Weight :392.49
- Boiling Point :550.4±50.0 °C(Predicted)
- Melting Point :212-215°C
- Purity :98%
Molecular Formula : C24H28N2O3 Canonical SMILES : CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C InChI : InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29) InChIKey : PURKAOJPTOLRMP-UHFFFAOYSA-N Solubility : solube in DMSO, Ethyl Acetate, Methanol Appearance : White to Light Brown Solid Application : Chloride Channel Agonists Storage : Store at -20°C Synonyms : N-[2,4-Bis[1,1-di(methyl)ethyl]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; Ivacaftor; Kalydeco; VX-770; VX 770; VX770
More details are to be found here
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Ivacaftor
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Properties:
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Last update 2024-05-03
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