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BGC > Product Search > WHI-P131 | 202475-60-3
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Suppliers for CAS

202475-60-3


Properties

CAS   202475-60-3 
Formula   C16H15N3O3 

Structure

6 Registered suppliers


Amadis Chemical Company Limited P.R.China
Leap Chem Co., Ltd P.R.China
Aea.ltd P.R.China
Molecular Formula: C16H15N3O3
Molecular Weight: 297.31
Hazard Symbols: Xi
WGKGermany: 3
BOC Sciences USA
AK Scientific, Inc. USA
Description :
A cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (Janus family kinase 3; IC50 = 78 µM). Has no effect on JAK1, JAK2, or Zap/Syk or Src tyrosine kinases. Acts as a potent inhibitor of glioblastoma cell adhesion and migration. Also reported to block thrombin-induced platelet aggregation.
  • Molecular Weight :297.31
  • Purity :> 98%
Molecular Formula :
C16H15N3O3
Canonical SMILES :
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC
InChI :
InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19)
InChIKey :
HOZUXBLMYUPGPZ-UHFFFAOYSA-N
Synonyms :
WHI-P131, WHI P-131, WHI P131, Janex 1
More details are to be found here
Santa Cruz Biotechnology, Inc. USA
Description :
A cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (Janus family kinase 3; IC50 = 78 µM). Has no effect on JAK1, JAK2, or Zap/Syk or Src tyrosine kinases. Acts as a potent inhibitor of glioblastoma cell adhesion and migration. Also reported to block thrombin-induced platelet aggregation.
  • Molecular Weight :297.31
  • Purity :> 98%
Molecular Formula :
C16H15N3O3
Canonical SMILES :
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC
InChI :
InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19)
InChIKey :
HOZUXBLMYUPGPZ-UHFFFAOYSA-N
Synonyms :
WHI-P131, WHI P-131, WHI P131, Janex 1
More details are to be found here

Detailed information on the suppliers of WHI-P131

Properties:

... more properties and specification on WHI-P131
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