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Suppliers for
Trametinib
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Properties | | CAS |
871700-17-3 | | Formula |
C26H23FIN5O4 |
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9 Registered suppliers
More details are to be found here
More details are to be found here
Molecular Formula: C26H23FIN5O4
Molecular Weight: 615.3947932
HS Code: 29339900
Molecular Formula: C26H23FIN5O4
Molecular Weight: 615.3947932
HS Code: 29339900
Molecular Formula: C26H23FIN5O4
Molecular Weight: 615.3947932
HS Code: 29339900
More details are to be found here
More details are to be found here
Description : A MEK inhibitor that suppresses MEK1 and MEK2 with IC50 of 0.92 and 1.8 nM and no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. It has been approved by FDA, in combination with Tafilnar, for the treatment of metastatic anaplastic thyroid cancer (ATC) with BRAF V600E mutation. - Molecular Weight :615.39
- Melting Point :299-301 °C
- Purity :≥98%
Molecular Formula : C26H23FIN5O4 Canonical SMILES : CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5
InChI :
InChI=1S/C26H23FIN5O4/c1-13-22-21(23(31(3)24(13)35)30-20-10-7-15(28)11-19(20)27)25(36)33(17-8-9-17)26(37)32(22)18-6-4-5-16(12-18)29-14(2)34/h4-7,10-12,17,30H,8-9H2,1-3H3,(H,29,34)
InChIKey :
LIRYPHYGHXZJBZ-UHFFFAOYSA-N
Appearance :
Off-White Solid
Synonyms :
GSK-1120212; GSK 1120212; GSK1120212; JTP74057; JTP 74057; JTP-74057; Mekinist
More details are to be found here
Description : A MEK inhibitor that suppresses MEK1 and MEK2 with IC50 of 0.92 and 1.8 nM and no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. It has been approved by FDA, in combination with Tafilnar, for the treatment of metastatic anaplastic thyroid cancer (ATC) with BRAF V600E mutation. - Molecular Weight :615.39
- Melting Point :299-301 °C
- Purity :≥98%
Molecular Formula : C26H23FIN5O4 Canonical SMILES : CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5
InChI :
InChI=1S/C26H23FIN5O4/c1-13-22-21(23(31(3)24(13)35)30-20-10-7-15(28)11-19(20)27)25(36)33(17-8-9-17)26(37)32(22)18-6-4-5-16(12-18)29-14(2)34/h4-7,10-12,17,30H,8-9H2,1-3H3,(H,29,34)
InChIKey :
LIRYPHYGHXZJBZ-UHFFFAOYSA-N
Appearance :
Off-White Solid
Synonyms :
GSK-1120212; GSK 1120212; GSK1120212; JTP74057; JTP 74057; JTP-74057; Mekinist
More details are to be found here
Detailed information on the suppliers of
Trametinib |
Properties:
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Last update 2024-05-13
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