BGC > Product Search > Tetracycline hydrochloride

Characteristics	A white or yellowish white powder .Odorless or almost.bygroscopic
Identification A B C	The positive reaction.
Solubility	Very soluble in water, insoluble in acetone , chloroform, ether.
Specific optical rotation	+53.5°~ +59.0°
Acidity of alkalinity	5.0~7.5
Impurity A	2%max
Impurity C	3% ~15%
Any other impurity	not more than the area of the principal peak in the chromatogram obtained with RS(B)5%
Total other impurity	not more than 3times the area of the principal peak in the chromatogram obtained with RS(B)15%
Disregard limit	ae of the principal peak in the chromatogram obtained with RS(C)1%
Loss on drying (pct)	max8.0
Sulphate	27.0-31.0%
Sulphated ash	1% max
Microcount limit test	NMT 500 col/g
Microcount-yeast and molds	NMT 10 col/g
Microcount-Escherichia coli	Absent
Microcount-Staphy lococcus aureus	Absent
Microcount-Pseudo monas	Absent
Assay	≥ 680I.U./mg (DRY)

Characteristics	A white or yellowish white powder .Odorless or almost.bygroscopic
Identification A B C	The positive reaction.
Solubility	Very soluble in water, insoluble in acetone , chloroform, ether.
Specific optical rotation	+53.5°~ +59.0°
Acidity of alkalinity	5.0~7.5
Impurity A	2%max
Impurity C	3% ~15%
Any other impurity	not more than the area of the principal peak in the chromatogram obtained with RS(B)5%
Total other impurity	not more than 3times the area of the principal peak in the chromatogram obtained with RS(B)15%
Disregard limit	ae of the principal peak in the chromatogram obtained with RS(C)1%
Loss on drying (pct)	max8.0
Sulphate	27.0-31.0%
Sulphated ash	1% max
Microcount limit test	NMT 500 col/g
Microcount-yeast and molds	NMT 10 col/g
Microcount-Escherichia coli	Absent
Microcount-Staphy lococcus aureus	Absent
Microcount-Pseudo monas	Absent
Assay	≥ 680I.U./mg (DRY)

Characteristics	A white or yellowish white powder .Odorless or almost.bygroscopic
Identification A B C	The positive reaction.
Solubility	Very soluble in water, insoluble in acetone , chloroform, ether.
Specific optical rotation	+53.5°~ +59.0°
Acidity of alkalinity	5.0~7.5
Impurity A	2%max
Impurity C	3% ~15%
Any other impurity	not more than the area of the principal peak in the chromatogram obtained with RS(B)5%
Total other impurity	not more than 3times the area of the principal peak in the chromatogram obtained with RS(B)15%
Disregard limit	ae of the principal peak in the chromatogram obtained with RS(C)1%
Loss on drying (pct)	max8.0
Sulphate	27.0-31.0%
Sulphated ash	1% max
Microcount limit test	NMT 500 col/g
Microcount-yeast and molds	NMT 10 col/g
Microcount-Escherichia coli	Absent
Microcount-Staphy lococcus aureus	Absent
Microcount-Pseudo monas	Absent
Assay	≥ 680I.U./mg (DRY)

Molecular Formula: C22H24N2O8.HCl
Molecular Weight: 480.90

Molecular Formula: C22H24N2O8.HCl
Molecular Weight: 480.90

Molecular Formula: C22H24N2O8.HCl
Molecular Weight: 480.90

Molecular Formula: C22H24N2O8.HCl
Molecular Weight: 480.90

Molecular Formula: C22H24N2O8.HCl
Molecular Weight: 480.90

USP/EP

Antibiotic

Alternative name	Tetracyclinhydrochlorid, API (mikrobielle Herkunft)
Further description	Tetracyclini hydrochloridum
Monograph	Ph.Eur.9.0
Pharmaceutical status	prescription only
UEXDES	Chemicals solid

Alternative name	Tetracyclinhydrochlorid, API (mikrobielle Herkunft)
Further description	Tetracyclini hydrochloridum
Monograph	Ph.Eur.9.0
Pharmaceutical status	prescription only
UEXDES	Chemicals solid

Alternative name	Tetracyclinhydrochlorid, API (mikrobielle Herkunft)
Further description	Tetracyclini hydrochloridum
Monograph	Ph.Eur.9.0
Pharmaceutical status	prescription only
UEXDES	Chemicals solid

Alternative name	Tetracyclinhydrochlorid, API (mikrobielle Herkunft)
Further description	Tetracyclini hydrochloridum
Monograph	Ph.Eur.9.0
Pharmaceutical status	prescription only
UEXDES	Chemicals solid

Alternative name	Tetracyclinhydrochlorid, API (mikrobielle Herkunft)
Further description	Tetracyclini hydrochloridum
Monograph	Ph.Eur.9.0
Pharmaceutical status	prescription only
UEXDES	Chemicals solid

Alternative name	Tetracyclinhydrochlorid, API (mikrobielle Herkunft)
Further description	Tetracyclini hydrochloridum
Monograph	Ph.Eur.9.0
Pharmaceutical status	prescription only
UEXDES	Chemicals solid

Description :
Tetracycline hydrochloride is the hydrochloride form of tetracycline, a broad-spectrum polyketide antibiotic. It inhibits protein synthesis in bacteria by blocking the binding of aminoacyl-tRNA to bacterial ribosomes. It can be used to treat infectious diseases caused by certain Gram-positive and -negative bacteria, Rickettsia, Mycoplasma, etc.

• Molecular Weight :480.90
• Boiling Point :799.4°C at 760 mmHg
• Melting Point :> 198°C (dec.)
• Purity :> 98%

Molecular Formula :
C22H24N2O8.HCl
Canonical SMILES :
CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
InChI :
InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChIKey :
YCIHPQHVWDULOY-FMZCEJRJSA-N
Solubility :
Soluble in Ethanol, Methanol, DMF, DMSO, Water
Appearance :
Light Yellow to Yellow Solid
Application :
Anti-Bacterial Agents
Storage : Store at -20°C
Synonyms :
HLS 831; HLS831; HLS-831; [4S-(4α,4aα,5aα,6β,12aα]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide Hydrochloride; (-)-Tetracycline Hydrochloride; Achromycin; Imex; Tetracyn

More details are to be found here

Description :
Tetracycline hydrochloride is the hydrochloride form of tetracycline, a broad-spectrum polyketide antibiotic. It inhibits protein synthesis in bacteria by blocking the binding of aminoacyl-tRNA to bacterial ribosomes. It can be used to treat infectious diseases caused by certain Gram-positive and -negative bacteria, Rickettsia, Mycoplasma, etc.

• Molecular Weight :480.90
• Boiling Point :799.4°C at 760 mmHg
• Melting Point :> 198°C (dec.)
• Purity :> 98%

Molecular Formula :
C22H24N2O8.HCl
Canonical SMILES :
CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
InChI :
InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChIKey :
YCIHPQHVWDULOY-FMZCEJRJSA-N
Solubility :
Soluble in Ethanol, Methanol, DMF, DMSO, Water
Appearance :
Light Yellow to Yellow Solid
Application :
Anti-Bacterial Agents
Storage : Store at -20°C
Synonyms :
HLS 831; HLS831; HLS-831; [4S-(4α,4aα,5aα,6β,12aα]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide Hydrochloride; (-)-Tetracycline Hydrochloride; Achromycin; Imex; Tetracyn

More details are to be found here

Description :
Tetracycline hydrochloride is the hydrochloride form of tetracycline, a broad-spectrum polyketide antibiotic. It inhibits protein synthesis in bacteria by blocking the binding of aminoacyl-tRNA to bacterial ribosomes. It can be used to treat infectious diseases caused by certain Gram-positive and -negative bacteria, Rickettsia, Mycoplasma, etc.

• Molecular Weight :480.90
• Boiling Point :799.4°C at 760 mmHg
• Melting Point :> 198°C (dec.)
• Purity :> 98%

Molecular Formula :
C22H24N2O8.HCl
Canonical SMILES :
CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
InChI :
InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChIKey :
YCIHPQHVWDULOY-FMZCEJRJSA-N
Solubility :
Soluble in Ethanol, Methanol, DMF, DMSO, Water
Appearance :
Light Yellow to Yellow Solid
Application :
Anti-Bacterial Agents
Storage : Store at -20°C
Synonyms :
HLS 831; HLS831; HLS-831; [4S-(4α,4aα,5aα,6β,12aα]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide Hydrochloride; (-)-Tetracycline Hydrochloride; Achromycin; Imex; Tetracyn

More details are to be found here

Description :
Tetracycline hydrochloride is the hydrochloride form of tetracycline, a broad-spectrum polyketide antibiotic. It inhibits protein synthesis in bacteria by blocking the binding of aminoacyl-tRNA to bacterial ribosomes. It can be used to treat infectious diseases caused by certain Gram-positive and -negative bacteria, Rickettsia, Mycoplasma, etc.

• Molecular Weight :480.90
• Boiling Point :799.4°C at 760 mmHg
• Melting Point :> 198°C (dec.)
• Purity :> 98%

Molecular Formula :
C22H24N2O8.HCl
Canonical SMILES :
CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
InChI :
InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChIKey :
YCIHPQHVWDULOY-FMZCEJRJSA-N
Solubility :
Soluble in Ethanol, Methanol, DMF, DMSO, Water
Appearance :
Light Yellow to Yellow Solid
Application :
Anti-Bacterial Agents
Storage : Store at -20°C
Synonyms :
HLS 831; HLS831; HLS-831; [4S-(4α,4aα,5aα,6β,12aα]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide Hydrochloride; (-)-Tetracycline Hydrochloride; Achromycin; Imex; Tetracyn

More details are to be found here

Description :
Tetracycline hydrochloride is the hydrochloride form of tetracycline, a broad-spectrum polyketide antibiotic. It inhibits protein synthesis in bacteria by blocking the binding of aminoacyl-tRNA to bacterial ribosomes. It can be used to treat infectious diseases caused by certain Gram-positive and -negative bacteria, Rickettsia, Mycoplasma, etc.

• Molecular Weight :480.90
• Boiling Point :799.4°C at 760 mmHg
• Melting Point :> 198°C (dec.)
• Purity :> 98%

Molecular Formula :
C22H24N2O8.HCl
Canonical SMILES :
CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
InChI :
InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChIKey :
YCIHPQHVWDULOY-FMZCEJRJSA-N
Solubility :
Soluble in Ethanol, Methanol, DMF, DMSO, Water
Appearance :
Light Yellow to Yellow Solid
Application :
Anti-Bacterial Agents
Storage : Store at -20°C
Synonyms :
HLS 831; HLS831; HLS-831; [4S-(4α,4aα,5aα,6β,12aα]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide Hydrochloride; (-)-Tetracycline Hydrochloride; Achromycin; Imex; Tetracyn

More details are to be found here

Description :
Tetracycline hydrochloride is the hydrochloride form of tetracycline, a broad-spectrum polyketide antibiotic. It inhibits protein synthesis in bacteria by blocking the binding of aminoacyl-tRNA to bacterial ribosomes. It can be used to treat infectious diseases caused by certain Gram-positive and -negative bacteria, Rickettsia, Mycoplasma, etc.

• Molecular Weight :480.90
• Boiling Point :799.4°C at 760 mmHg
• Melting Point :> 198°C (dec.)
• Purity :> 98%

Molecular Formula :
C22H24N2O8.HCl
Canonical SMILES :
CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
InChI :
InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChIKey :
YCIHPQHVWDULOY-FMZCEJRJSA-N
Solubility :
Soluble in Ethanol, Methanol, DMF, DMSO, Water
Appearance :
Light Yellow to Yellow Solid
Application :
Anti-Bacterial Agents
Storage : Store at -20°C
Synonyms :
HLS 831; HLS831; HLS-831; [4S-(4α,4aα,5aα,6β,12aα]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide Hydrochloride; (-)-Tetracycline Hydrochloride; Achromycin; Imex; Tetracyn

More details are to be found here

Description :
Tetracycline hydrochloride is the hydrochloride form of tetracycline, a broad-spectrum polyketide antibiotic. It inhibits protein synthesis in bacteria by blocking the binding of aminoacyl-tRNA to bacterial ribosomes. It can be used to treat infectious diseases caused by certain Gram-positive and -negative bacteria, Rickettsia, Mycoplasma, etc.

• Molecular Weight :480.90
• Boiling Point :799.4°C at 760 mmHg
• Melting Point :> 198°C (dec.)
• Purity :> 98%

Molecular Formula :
C22H24N2O8.HCl
Canonical SMILES :
CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
InChI :
InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChIKey :
YCIHPQHVWDULOY-FMZCEJRJSA-N
Solubility :
Soluble in Ethanol, Methanol, DMF, DMSO, Water
Appearance :
Light Yellow to Yellow Solid
Application :
Anti-Bacterial Agents
Storage : Store at -20°C
Synonyms :
HLS 831; HLS831; HLS-831; [4S-(4α,4aα,5aα,6β,12aα]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide Hydrochloride; (-)-Tetracycline Hydrochloride; Achromycin; Imex; Tetracyn

More details are to be found here

Description :
Tetracycline hydrochloride is the hydrochloride form of tetracycline, a broad-spectrum polyketide antibiotic. It inhibits protein synthesis in bacteria by blocking the binding of aminoacyl-tRNA to bacterial ribosomes. It can be used to treat infectious diseases caused by certain Gram-positive and -negative bacteria, Rickettsia, Mycoplasma, etc.

• Molecular Weight :480.90
• Boiling Point :799.4°C at 760 mmHg
• Melting Point :> 198°C (dec.)
• Purity :> 98%

Molecular Formula :
C22H24N2O8.HCl
Canonical SMILES :
CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
InChI :
InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChIKey :
YCIHPQHVWDULOY-FMZCEJRJSA-N
Solubility :
Soluble in Ethanol, Methanol, DMF, DMSO, Water
Appearance :
Light Yellow to Yellow Solid
Application :
Anti-Bacterial Agents
Storage : Store at -20°C
Synonyms :
HLS 831; HLS831; HLS-831; [4S-(4α,4aα,5aα,6β,12aα]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide Hydrochloride; (-)-Tetracycline Hydrochloride; Achromycin; Imex; Tetracyn

More details are to be found here

Description :
Tetracycline hydrochloride is the hydrochloride form of tetracycline, a broad-spectrum polyketide antibiotic. It inhibits protein synthesis in bacteria by blocking the binding of aminoacyl-tRNA to bacterial ribosomes. It can be used to treat infectious diseases caused by certain Gram-positive and -negative bacteria, Rickettsia, Mycoplasma, etc.

• Molecular Weight :480.90
• Boiling Point :799.4°C at 760 mmHg
• Melting Point :> 198°C (dec.)
• Purity :> 98%

Molecular Formula :
C22H24N2O8.HCl
Canonical SMILES :
CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
InChI :
InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChIKey :
YCIHPQHVWDULOY-FMZCEJRJSA-N
Solubility :
Soluble in Ethanol, Methanol, DMF, DMSO, Water
Appearance :
Light Yellow to Yellow Solid
Application :
Anti-Bacterial Agents
Storage : Store at -20°C
Synonyms :
HLS 831; HLS831; HLS-831; [4S-(4α,4aα,5aα,6β,12aα]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide Hydrochloride; (-)-Tetracycline Hydrochloride; Achromycin; Imex; Tetracyn

More details are to be found here

Description :
Tetracycline hydrochloride is the hydrochloride form of tetracycline, a broad-spectrum polyketide antibiotic. It inhibits protein synthesis in bacteria by blocking the binding of aminoacyl-tRNA to bacterial ribosomes. It can be used to treat infectious diseases caused by certain Gram-positive and -negative bacteria, Rickettsia, Mycoplasma, etc.

• Molecular Weight :480.90
• Boiling Point :799.4°C at 760 mmHg
• Melting Point :> 198°C (dec.)
• Purity :> 98%

Molecular Formula :
C22H24N2O8.HCl
Canonical SMILES :
CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
InChI :
InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChIKey :
YCIHPQHVWDULOY-FMZCEJRJSA-N
Solubility :
Soluble in Ethanol, Methanol, DMF, DMSO, Water
Appearance :
Light Yellow to Yellow Solid
Application :
Anti-Bacterial Agents
Storage : Store at -20°C
Synonyms :
HLS 831; HLS831; HLS-831; [4S-(4α,4aα,5aα,6β,12aα]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide Hydrochloride; (-)-Tetracycline Hydrochloride; Achromycin; Imex; Tetracyn

More details are to be found here