BGC > Product Search > Fenretinide

Molecular Formula: C26H33NO2
Molecular Weight: 391,55

Molecular Formula: C26H33NO2
Molecular Weight: 391,55

Description :
Fenretinide is an orally-active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell differentiation and apoptosis in some tumor cell types. This agent also inhibits tumor growth by modulating angiogenesis-associated growth factors and their receptors and exhibits retinoid receptor-independent apoptotic properties.

• Molecular Weight :391.54572
• Melting Point :162-163°C
• Purity :> 95%

Molecular Formula :
C26H33NO2
Canonical SMILES :
CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)NC2=CC=C(C=C2)O)C)C
InChI :
InChI=1S/C26H33NO2/c1-19(11-16-24-21(3)10-7-17-26(24,4)5)8-6-9-20(2)18-25(29)27-22-12-14-23(28)15-13-22/h6,8-9,11-16,18,28H,7,10,17H2,1-5H3,(H,27,29)/b9-6+,16-11+,19-8+,20-18+
InChIKey :
AKJHMTWEGVYYSE-FXILSDISSA-N
Appearance :
Yellow Solid
Application :
Anticarcinogenic Agents
Synonyms :
4-HPR; McNR-1967; McNR1967; McNR 1967; HPR; Fenretinide. N-(4-Hydroxyphenyl)retinamide; 4-HPR; 4-hydroxyphenylretinamide; 4-Hydroxyphenyl retinamide

More details are to be found here

Description :
Fenretinide is an orally-active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell differentiation and apoptosis in some tumor cell types. This agent also inhibits tumor growth by modulating angiogenesis-associated growth factors and their receptors and exhibits retinoid receptor-independent apoptotic properties.

• Molecular Weight :391.54572
• Melting Point :162-163°C
• Purity :> 95%

Molecular Formula :
C26H33NO2
Canonical SMILES :
CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)NC2=CC=C(C=C2)O)C)C
InChI :
InChI=1S/C26H33NO2/c1-19(11-16-24-21(3)10-7-17-26(24,4)5)8-6-9-20(2)18-25(29)27-22-12-14-23(28)15-13-22/h6,8-9,11-16,18,28H,7,10,17H2,1-5H3,(H,27,29)/b9-6+,16-11+,19-8+,20-18+
InChIKey :
AKJHMTWEGVYYSE-FXILSDISSA-N
Appearance :
Yellow Solid
Application :
Anticarcinogenic Agents
Synonyms :
4-HPR; McNR-1967; McNR1967; McNR 1967; HPR; Fenretinide. N-(4-Hydroxyphenyl)retinamide; 4-HPR; 4-hydroxyphenylretinamide; 4-Hydroxyphenyl retinamide

More details are to be found here

Description :
Fenretinide is an orally-active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell differentiation and apoptosis in some tumor cell types. This agent also inhibits tumor growth by modulating angiogenesis-associated growth factors and their receptors and exhibits retinoid receptor-independent apoptotic properties.

• Molecular Weight :391.54572
• Melting Point :162-163°C
• Purity :> 95%

Molecular Formula :
C26H33NO2
Canonical SMILES :
CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)NC2=CC=C(C=C2)O)C)C
InChI :
InChI=1S/C26H33NO2/c1-19(11-16-24-21(3)10-7-17-26(24,4)5)8-6-9-20(2)18-25(29)27-22-12-14-23(28)15-13-22/h6,8-9,11-16,18,28H,7,10,17H2,1-5H3,(H,27,29)/b9-6+,16-11+,19-8+,20-18+
InChIKey :
AKJHMTWEGVYYSE-FXILSDISSA-N
Appearance :
Yellow Solid
Application :
Anticarcinogenic Agents
Synonyms :
4-HPR; McNR-1967; McNR1967; McNR 1967; HPR; Fenretinide. N-(4-Hydroxyphenyl)retinamide; 4-HPR; 4-hydroxyphenylretinamide; 4-Hydroxyphenyl retinamide

More details are to be found here