BGC > Product Search > Ezetimibe ketone

Description :
Phase-I metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes.

• Molecular Weight :407.42
• Melting Point :> 57 °C
• Purity :> 95%

Molecular Formula :
C24H19F2NO3
Canonical SMILES :
C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(=O)C4=CC=C(C=C4)F)O
Appearance :
White to Off-White Solid
Synonyms :
(3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone;

More details are to be found here

Description :
Phase-I metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes.

• Molecular Weight :407.42
• Melting Point :> 57 °C
• Purity :> 95%

Molecular Formula :
C24H19F2NO3
Canonical SMILES :
C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(=O)C4=CC=C(C=C4)F)O
Appearance :
White to Off-White Solid
Synonyms :
(3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone;

More details are to be found here