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BGC > Product Search > Cilastatin sodium | 81129-83-1
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Suppliers for CAS

81129-83-1



 

Properties

CAS   81129-83-1 
Formula   C16H25N2NaO5
EINECS   279-694-4 

Structure

14 Registered suppliers


Simagchem Corporation P.R.China
Dayang Chem (Hangzhou) Co.,Ltd. P.R.China
Xingrui Industry Co., Limited P.R.China
Leap Chem Co., Ltd P.R.China
Shandong Minglang Chemical Co., Ltd P.R.China
Molecular Formula: C16H25N2O5S.Na
Molecular Weight: 380.44
More details are to be found here
Hangzhou Zhongqi Chem Co., Ltd P.R.China
Molecular Formula: C16H25N2O5S.Na
Molecular Weight: 380.44
More details are to be found here
Molecular Formula: C16H25N2O5S.Na
Molecular Weight: 380.44
More details are to be found here
Lori Industry Co., Ltd P.R.China
Molecular Formula: C16H25N2O5S.Na
Molecular Weight: 380.44
More details are to be found here
Skyrun Industrial Co., Ltd. P.R.China
Molecular Formula: C16H25N2O5S.Na
Molecular Weight: 380.44
More details are to be found here
BOC Sciences USA
Xiamen Equation Chemical Co.,Ltd P.R.China
Description :
Cilastatin sodium is the sodium salt of cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects.
  • Molecular Weight :380.43
  • Purity :≥99% by HPLC
Molecular Formula :
C16H25N2NaO5S
Canonical SMILES :
CC1(CC1C(=O)NC(=CCCCCSCC(C(=O)O)N)C(=O)[O-])C.[Na+]
InChI :
InChI=1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11+;/m1./s1
InChIKey :
QXPBTTUOVWMPJN-QBNHLFMHSA-M
Synonyms :
L 642957; MK 791; L642957; MK791; L-642957; MK-791; [R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic Acid Monosodium Salt; (2Z)​-7-​[[(2R)​-​2-​Amino-​2-​carboxyethyl]​thio]​-​2-​[[[(1S)​-​2,​2-​dimethylcyclopropyl]​carbonyl]​amino]​-​2-heptenoic Acid Sodium Salt; sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate
More details are to be found here
AK Scientific, Inc. USA
Description :
Cilastatin sodium is the sodium salt of cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects.
  • Molecular Weight :380.43
  • Purity :≥99% by HPLC
Molecular Formula :
C16H25N2NaO5S
Canonical SMILES :
CC1(CC1C(=O)NC(=CCCCCSCC(C(=O)O)N)C(=O)[O-])C.[Na+]
InChI :
InChI=1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11+;/m1./s1
InChIKey :
QXPBTTUOVWMPJN-QBNHLFMHSA-M
Synonyms :
L 642957; MK 791; L642957; MK791; L-642957; MK-791; [R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic Acid Monosodium Salt; (2Z)​-7-​[[(2R)​-​2-​Amino-​2-​carboxyethyl]​thio]​-​2-​[[[(1S)​-​2,​2-​dimethylcyclopropyl]​carbonyl]​amino]​-​2-heptenoic Acid Sodium Salt; sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate
More details are to be found here
Chemos GmbH & Co. KG Germany
Description :
Cilastatin sodium is the sodium salt of cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects.
  • Molecular Weight :380.43
  • Purity :≥99% by HPLC
Molecular Formula :
C16H25N2NaO5S
Canonical SMILES :
CC1(CC1C(=O)NC(=CCCCCSCC(C(=O)O)N)C(=O)[O-])C.[Na+]
InChI :
InChI=1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11+;/m1./s1
InChIKey :
QXPBTTUOVWMPJN-QBNHLFMHSA-M
Synonyms :
L 642957; MK 791; L642957; MK791; L-642957; MK-791; [R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic Acid Monosodium Salt; (2Z)​-7-​[[(2R)​-​2-​Amino-​2-​carboxyethyl]​thio]​-​2-​[[[(1S)​-​2,​2-​dimethylcyclopropyl]​carbonyl]​amino]​-​2-heptenoic Acid Sodium Salt; sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate
More details are to be found here
BuGuCh & Partners Germany
Description :
Cilastatin sodium is the sodium salt of cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects.
  • Molecular Weight :380.43
  • Purity :≥99% by HPLC
Molecular Formula :
C16H25N2NaO5S
Canonical SMILES :
CC1(CC1C(=O)NC(=CCCCCSCC(C(=O)O)N)C(=O)[O-])C.[Na+]
InChI :
InChI=1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11+;/m1./s1
InChIKey :
QXPBTTUOVWMPJN-QBNHLFMHSA-M
Synonyms :
L 642957; MK 791; L642957; MK791; L-642957; MK-791; [R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic Acid Monosodium Salt; (2Z)​-7-​[[(2R)​-​2-​Amino-​2-​carboxyethyl]​thio]​-​2-​[[[(1S)​-​2,​2-​dimethylcyclopropyl]​carbonyl]​amino]​-​2-heptenoic Acid Sodium Salt; sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate
More details are to be found here
Santa Cruz Biotechnology, Inc. USA
Description :
Cilastatin sodium is the sodium salt of cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects.
  • Molecular Weight :380.43
  • Purity :≥99% by HPLC
Molecular Formula :
C16H25N2NaO5S
Canonical SMILES :
CC1(CC1C(=O)NC(=CCCCCSCC(C(=O)O)N)C(=O)[O-])C.[Na+]
InChI :
InChI=1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11+;/m1./s1
InChIKey :
QXPBTTUOVWMPJN-QBNHLFMHSA-M
Synonyms :
L 642957; MK 791; L642957; MK791; L-642957; MK-791; [R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic Acid Monosodium Salt; (2Z)​-7-​[[(2R)​-​2-​Amino-​2-​carboxyethyl]​thio]​-​2-​[[[(1S)​-​2,​2-​dimethylcyclopropyl]​carbonyl]​amino]​-​2-heptenoic Acid Sodium Salt; sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate
More details are to be found here

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Properties:

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