BGC > Product Search > N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea | 1020172-07-9
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Suppliers for CAS
1020172-07-9
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Properties | | CAS |
1020172-07-9 | | Formula |
C30H28FN7O3 |
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7 Registered suppliers
Amadis Chemical Company Limited
P.R.China
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C30H28FN7O3
Molecular Weight: 554
JieJie Group Co., Ltd.
P.R.China
Molecular Formula: C30H28FN7O3
Molecular Weight: 554
Aea.ltd
P.R.China
Molecular Formula: C30H28FN7O3
Molecular Weight: 554
Molecular Formula: C30H28FN7O3
Molecular Weight: 554
BOC Sciences
USA
Description : Rebastinib is an orally bioactive inhibitor of Bcr-Abl that binds to and inhibits Bcr-Abl fusion oncoprotein. Rebastinib changes the conformation of the folded protein to disallow ligand-dependent and ligand-independent activation. It also exhibits inhibitory activity at SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2. - Molecular Weight :553.598
- Melting Point :> 181°C (dec.)
- Purity :≥98%
Molecular Formula : C30H28FN7O3 Canonical SMILES : CC(C)(C)C1=NN(C(=C1)NC(=O)NC2=C(C=C(C=C2)OC3=CC(=NC=C3)C(=O)NC)F)C4=CC5=C(C=C4)N=CC=C5
InChI :
InChI=1S/C30H28FN7O3/c1-30(2,3)26-17-27(38(37-26)19-7-9-23-18(14-19)6-5-12-33-23)36-29(40)35-24-10-8-20(15-22(24)31)41-21-11-13-34-25(16-21)28(39)32-4/h5-17H,1-4H3,(H,32,39)(H2,35,36,40)
InChIKey :
WVXNSAVVKYZVOE-UHFFFAOYSA-N
Appearance :
Off-White Solid
Application :
Antineoplastic Agents
Synonyms :
DCC2036; DCC-2036; DCC 2036; Rebastinib. 4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
More details are to be found here
Chemos GmbH & Co. KG
Germany
Description : Rebastinib is an orally bioactive inhibitor of Bcr-Abl that binds to and inhibits Bcr-Abl fusion oncoprotein. Rebastinib changes the conformation of the folded protein to disallow ligand-dependent and ligand-independent activation. It also exhibits inhibitory activity at SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2. - Molecular Weight :553.598
- Melting Point :> 181°C (dec.)
- Purity :≥98%
Molecular Formula : C30H28FN7O3 Canonical SMILES : CC(C)(C)C1=NN(C(=C1)NC(=O)NC2=C(C=C(C=C2)OC3=CC(=NC=C3)C(=O)NC)F)C4=CC5=C(C=C4)N=CC=C5
InChI :
InChI=1S/C30H28FN7O3/c1-30(2,3)26-17-27(38(37-26)19-7-9-23-18(14-19)6-5-12-33-23)36-29(40)35-24-10-8-20(15-22(24)31)41-21-11-13-34-25(16-21)28(39)32-4/h5-17H,1-4H3,(H,32,39)(H2,35,36,40)
InChIKey :
WVXNSAVVKYZVOE-UHFFFAOYSA-N
Appearance :
Off-White Solid
Application :
Antineoplastic Agents
Synonyms :
DCC2036; DCC-2036; DCC 2036; Rebastinib. 4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
More details are to be found here
Santa Cruz Biotechnology, Inc.
USA
Description : Rebastinib is an orally bioactive inhibitor of Bcr-Abl that binds to and inhibits Bcr-Abl fusion oncoprotein. Rebastinib changes the conformation of the folded protein to disallow ligand-dependent and ligand-independent activation. It also exhibits inhibitory activity at SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2. - Molecular Weight :553.598
- Melting Point :> 181°C (dec.)
- Purity :≥98%
Molecular Formula : C30H28FN7O3 Canonical SMILES : CC(C)(C)C1=NN(C(=C1)NC(=O)NC2=C(C=C(C=C2)OC3=CC(=NC=C3)C(=O)NC)F)C4=CC5=C(C=C4)N=CC=C5
InChI :
InChI=1S/C30H28FN7O3/c1-30(2,3)26-17-27(38(37-26)19-7-9-23-18(14-19)6-5-12-33-23)36-29(40)35-24-10-8-20(15-22(24)31)41-21-11-13-34-25(16-21)28(39)32-4/h5-17H,1-4H3,(H,32,39)(H2,35,36,40)
InChIKey :
WVXNSAVVKYZVOE-UHFFFAOYSA-N
Appearance :
Off-White Solid
Application :
Antineoplastic Agents
Synonyms :
DCC2036; DCC-2036; DCC 2036; Rebastinib. 4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
More details are to be found here
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