BGC > Product Search > Decursin | 5928-25-6

Molecular Formula: C19H20O5
Molecular Weight: 328.36
WGKGermany: 3
HS Code: 29322090

Description :
Decursin is a coumarin from The roots of Peucedanum ostruthium. Coumarins, such as decursinol and decursin, are known to be the major compounds of A. gigas. Angelica gigas roots have been widely used traditionally in Korean herbal medicine not only for the treatment of anaemia, but also as a sedative, an anodyne and a tonic. Studies have shown that decursin inhibits VEGF-mediated inner BRB breakdown through suppression of VEGFR-2 signaling pathway. And decursin is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug.

• Molecular Weight :328.36
• Boiling Point :469.4±45.0 °C | Condition: Press: 760 Torr
• Purity :> 98%

Molecular Formula :
C19H20O5
Canonical SMILES :
CC(=CC(=O)OC1CC2=C(C=C3C(=C2)C=CC(=O)O3)OC1(C)C)C
InChI :
InChI=1S/C19H20O5/c1-11(2)7-18(21)23-16-9-13-8-12-5-6-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/t16-/m0/s1
InChIKey :
CUKSFECWKQBVED-INIZCTEOSA-N
Solubility :
Soluble to 5 mg/mL in DMSO
Appearance :
White to beige solid powder
Application :
Enzyme Activators
Storage : 2 - 8 °C, keep away from light.
Synonyms :
2-Butenoic acid, 3-methyl-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester (9CI); 2-Butenoic acid, 3-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester, (S)-; Crotonic acid, 3-methyl-, ester with 7,8-dihydro-7-hydroxy-8,8-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one, (+)- (8CI); 2H,6H-Benzo[1,2-b:5,4-b']dipyran, 2-butenoic acid deriv.

More details are to be found here

Description :
Decursin is a coumarin from The roots of Peucedanum ostruthium. Coumarins, such as decursinol and decursin, are known to be the major compounds of A. gigas. Angelica gigas roots have been widely used traditionally in Korean herbal medicine not only for the treatment of anaemia, but also as a sedative, an anodyne and a tonic. Studies have shown that decursin inhibits VEGF-mediated inner BRB breakdown through suppression of VEGFR-2 signaling pathway. And decursin is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug.

• Molecular Weight :328.36
• Boiling Point :469.4±45.0 °C | Condition: Press: 760 Torr
• Purity :> 98%

Molecular Formula :
C19H20O5
Canonical SMILES :
CC(=CC(=O)OC1CC2=C(C=C3C(=C2)C=CC(=O)O3)OC1(C)C)C
InChI :
InChI=1S/C19H20O5/c1-11(2)7-18(21)23-16-9-13-8-12-5-6-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/t16-/m0/s1
InChIKey :
CUKSFECWKQBVED-INIZCTEOSA-N
Solubility :
Soluble to 5 mg/mL in DMSO
Appearance :
White to beige solid powder
Application :
Enzyme Activators
Storage : 2 - 8 °C, keep away from light.
Synonyms :
2-Butenoic acid, 3-methyl-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester (9CI); 2-Butenoic acid, 3-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester, (S)-; Crotonic acid, 3-methyl-, ester with 7,8-dihydro-7-hydroxy-8,8-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one, (+)- (8CI); 2H,6H-Benzo[1,2-b:5,4-b']dipyran, 2-butenoic acid deriv.

More details are to be found here

Description :
Decursin is a coumarin from The roots of Peucedanum ostruthium. Coumarins, such as decursinol and decursin, are known to be the major compounds of A. gigas. Angelica gigas roots have been widely used traditionally in Korean herbal medicine not only for the treatment of anaemia, but also as a sedative, an anodyne and a tonic. Studies have shown that decursin inhibits VEGF-mediated inner BRB breakdown through suppression of VEGFR-2 signaling pathway. And decursin is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug.

• Molecular Weight :328.36
• Boiling Point :469.4±45.0 °C | Condition: Press: 760 Torr
• Purity :> 98%

Molecular Formula :
C19H20O5
Canonical SMILES :
CC(=CC(=O)OC1CC2=C(C=C3C(=C2)C=CC(=O)O3)OC1(C)C)C
InChI :
InChI=1S/C19H20O5/c1-11(2)7-18(21)23-16-9-13-8-12-5-6-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/t16-/m0/s1
InChIKey :
CUKSFECWKQBVED-INIZCTEOSA-N
Solubility :
Soluble to 5 mg/mL in DMSO
Appearance :
White to beige solid powder
Application :
Enzyme Activators
Storage : 2 - 8 °C, keep away from light.
Synonyms :
2-Butenoic acid, 3-methyl-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester (9CI); 2-Butenoic acid, 3-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester, (S)-; Crotonic acid, 3-methyl-, ester with 7,8-dihydro-7-hydroxy-8,8-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one, (+)- (8CI); 2H,6H-Benzo[1,2-b:5,4-b']dipyran, 2-butenoic acid deriv.

More details are to be found here