BGC > Product Search > N'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide | 849217-68-1

Molecular Formula: C28H24FN3O5
Molecular Weight: 502

Molecular Formula: C28H24FN3O5
Molecular Weight: 502

Molecular Formula: C28H24FN3O5
Molecular Weight: 502

Molecular Formula: C28H24FN3O5
Molecular Weight: 502

Molecular Formula: C28H24FN3O5
Molecular Weight: 502

Description :
Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.

• Molecular Weight :501.51
• Purity :> 98%

Molecular Formula :
C28H24FN3O5
Canonical SMILES :
COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F
InChI :
InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34)
InChIKey :
ONIQOQHATWINJY-UHFFFAOYSA-N
Appearance :
White to Light Yellow Powder
Storage : - 20 °C

More details are to be found here

Description :
Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.

• Molecular Weight :501.51
• Purity :> 98%

Molecular Formula :
C28H24FN3O5
Canonical SMILES :
COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F
InChI :
InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34)
InChIKey :
ONIQOQHATWINJY-UHFFFAOYSA-N
Appearance :
White to Light Yellow Powder
Storage : - 20 °C

More details are to be found here

MF: C28H24FN3O5
MW: 501,51

Purity : 98%
Smile code : O=C(C1(C(NC2=CC=C(F)C=C2)=O)CC1)NC3=CC=C(OC4=CC=NC5=CC(OC)=C(OC)C=C45)C=C3
MDL Number : MFCD20926324
MolFormula : C28H24FN3O5
MolWeight : 501.5057
Available in stock : 79.298

More details are to be found here

Smile code:
O=C(C1(C(NC2=CC=C(F)C=C2)=O)CC1)NC3=CC=C(OC4=CC=NC5=CC(OC)=C(OC)C=C45)C=C3
MDL Number:
MFCD20926324
Purity :
98%
Available in stock:
66.146 g

More details are to be found here

Smile code:
O=C(C1(C(NC2=CC=C(F)C=C2)=O)CC1)NC3=CC=C(OC4=CC=NC5=CC(OC)=C(OC)C=C45)C=C3
MDL Number:
MFCD20926324
Purity :
98%
Available in stock:
66.146 g

More details are to be found here

Smile code:
O=C(C1(C(NC2=CC=C(F)C=C2)=O)CC1)NC3=CC=C(OC4=CC=NC5=CC(OC)=C(OC)C=C45)C=C3
MDL Number:
MFCD20926324
Purity :
98%
Available in stock:
66.146 g

More details are to be found here

Smile code:
O=C(C1(C(NC2=CC=C(F)C=C2)=O)CC1)NC3=CC=C(OC4=CC=NC5=CC(OC)=C(OC)C=C45)C=C3
MDL Number:
MFCD20926324
Purity :
98%
Available in stock:
66.146 g

More details are to be found here