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BGC > Product Search > Tofacitinib | 477600-75-2
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Suppliers for CAS

477600-75-2


Properties

CAS   477600-75-2 
Formula   C16H20N6

Structure

21 Registered suppliers


Simagchem Corporation P.R.China
Amadis Chemical Company Limited P.R.China
Hangzhou Keying Chem Co., Ltd. P.R.China

More details are to be found here
Xingrui Industry Co., Limited P.R.China

More details are to be found here
Hangzhou Meite Industry Co., Ltd (Hangzhou Meite Chemical Co., Ltd) P.R.China

More details are to be found here
Capot Chemical Co., Ltd. P.R.China
Leap Chem Co., Ltd P.R.China
Shanghai Haoyuan Chemexpress Co., Ltd. P.R.China
Arakato Development Ltd Hong Kong
Purity: 99%
FUDAW INDUSTRY LTD P.R.China
Purity: 99%
Create Chemical Co., Ltd. P.R.China
Purity: 99%
Shandong Lanhai Industry Co.,Ltd. P.R.China
Purity: 99%
Hangzhou Zhongqi Chem Co., Ltd P.R.China
Purity: 99%
Purity: 99%
Nantong Xindao Biotech Ltd P.R.China
Purity: 99%
Finetech Industry Limited P.R.China
Skyrun Industrial Co., Ltd. P.R.China

More details are to be found here
BOC Sciences USA
AK Scientific, Inc. USA
Description :
Tofacitinib is an orally available JAK3 inhibitor (IC50 = 1 nM), exhibiting 20- and 100-fold less potency against JAK2 and JAK1. Tofacitinib induces G1 cell cycle arrest and inhibits tumor growth in Epstein-Barr virus-associated T and natural killer cell lymphoma cells. It is approved for the treatment of rheumatoid arthritis (RA).
  • Molecular Weight :312.37
  • Purity :> 98%
Molecular Formula :
C16H20N6O
Canonical SMILES :
CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
InChI :
InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13+/m1/s1
InChIKey :
UJLAWZDWDVHWOW-YPMHNXCESA-N
Synonyms :
Tasocitinib; 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile; CP-690550
More details are to be found here
Chemos GmbH & Co. KG Germany
Description :
Tofacitinib is an orally available JAK3 inhibitor (IC50 = 1 nM), exhibiting 20- and 100-fold less potency against JAK2 and JAK1. Tofacitinib induces G1 cell cycle arrest and inhibits tumor growth in Epstein-Barr virus-associated T and natural killer cell lymphoma cells. It is approved for the treatment of rheumatoid arthritis (RA).
  • Molecular Weight :312.37
  • Purity :> 98%
Molecular Formula :
C16H20N6O
Canonical SMILES :
CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
InChI :
InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13+/m1/s1
InChIKey :
UJLAWZDWDVHWOW-YPMHNXCESA-N
Synonyms :
Tasocitinib; 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile; CP-690550
More details are to be found here
CM Fine Chemicals Switzerland
Description :
Tofacitinib is an orally available JAK3 inhibitor (IC50 = 1 nM), exhibiting 20- and 100-fold less potency against JAK2 and JAK1. Tofacitinib induces G1 cell cycle arrest and inhibits tumor growth in Epstein-Barr virus-associated T and natural killer cell lymphoma cells. It is approved for the treatment of rheumatoid arthritis (RA).
  • Molecular Weight :312.37
  • Purity :> 98%
Molecular Formula :
C16H20N6O
Canonical SMILES :
CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
InChI :
InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13+/m1/s1
InChIKey :
UJLAWZDWDVHWOW-YPMHNXCESA-N
Synonyms :
Tasocitinib; 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile; CP-690550
More details are to be found here
Santa Cruz Biotechnology, Inc. USA
Description :
Tofacitinib is an orally available JAK3 inhibitor (IC50 = 1 nM), exhibiting 20- and 100-fold less potency against JAK2 and JAK1. Tofacitinib induces G1 cell cycle arrest and inhibits tumor growth in Epstein-Barr virus-associated T and natural killer cell lymphoma cells. It is approved for the treatment of rheumatoid arthritis (RA).
  • Molecular Weight :312.37
  • Purity :> 98%
Molecular Formula :
C16H20N6O
Canonical SMILES :
CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
InChI :
InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13+/m1/s1
InChIKey :
UJLAWZDWDVHWOW-YPMHNXCESA-N
Synonyms :
Tasocitinib; 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile; CP-690550
More details are to be found here

Detailed information on the suppliers of Tofacitinib

Properties:

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