BGC > Product Search > (E)-2-Cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)prop-2-enethioamide | 148741-30-4

Molecular Formula: C18H24N2OS
Molecular Weight: 316.46
WGKGermany: 3
HS Code: 29309090

Molecular Formula: C18H24N2OS
Molecular Weight: 316.46
WGKGermany: 3
HS Code: 29309090

Description :
AG-879, a tyrphostin compound, is a dual EGFR/HER2 inhibitor that was administered together with androgen withdrawal therapy. It inhibits nerve growth factor (NGF)-dependent TrkA tyrosine phosphorylation in PC-12 cells (IC50 = ~40 μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM), and the VEGF receptor FLK1 (IC50 = ~1 μM).

• Molecular Weight :316.5

Molecular Formula :
C18H24N2OS
Canonical SMILES :
CC(C)(C)C1=CC(=CC(=C(N)S)C#N)C=C(C1=O)C(C)(C)C
InChI :
InChI=1S/C18H24N2OS/c1-17(2,3)13-8-11(7-12(10-19)16(20)22)9-14(15(13)21)18(4,5)6/h7-9,22H,20H2,1-6H3/b16-12+
InChIKey :
LCUMYVYIHXYBIA-FOWTUZBSSA-N
Solubility :
DMSO to 100 mM; ethanol to 25 mM
Appearance :
Yellow solid
Synonyms :
α-Cyano-(3,5-di-t-butyl-4-hydroxy)thiocinnamide

More details are to be found here

Purity : 95%
Smile code : S=C(N)/C(C#N)=C/C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1
MDL Number : MFCD00236450
MolFormula : C18H24N2OS
MolWeight : 316.4610
Available in stock : 1.223

More details are to be found here

Smile code:
S=C(N)/C(C#N)=C/C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1
MDL Number:
MFCD00236450
Purity :
95%
Available in stock:
11.141 g

More details are to be found here

Smile code:
S=C(N)/C(C#N)=C/C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1
MDL Number:
MFCD00236450
Purity :
95%
Available in stock:
11.141 g

More details are to be found here