BGC > Product Search > Lomeguatrib | 192441-08-0

Molecular Formula: C10H8BrN5OS
Molecular Weight: 326.17
Hazard Symbols: Xn
WGKGermany: 3

Molecular Formula: C10H8BrN5OS
Molecular Weight: 326.17
Hazard Symbols: Xn
WGKGermany: 3

Molecular Formula: C10H8BrN5OS
Molecular Weight: 326.17
Hazard Symbols: Xn
WGKGermany: 3

Description :
Lomeguatrib, also known as PaTrin-2, is a potent Inhibitor of O6-Alkylguanine-DNA-Alkyltransferase. Lomeguatrib is also a nontoxic low-molecular weight pseudosubstrate that has the ability to inactivate MGMT. Lomeguatrib can be used with temozolomide (TMZ) for GBM treatment.

• Molecular Weight :326.172

Molecular Formula :
C10H8BrN5OS
Canonical SMILES :
C1=C(SC=C1Br)COC2=NC(=NC3=C2NC=N3)N
InChI :
InChI=1S/C10H8BrN5OS/c11-5-1-6(18-3-5)2-17-9-7-8(14-4-13-7)15-10(12)16-9/h1,3-4H,2H2,(H3,12,13,14,15,16)
InChIKey :
JUJPKFNFCWJBCX-UHFFFAOYSA-N
Appearance :
white solid powder
Synonyms :
PaTrin 2; PaTrin2; PaTrin-2; Lomeguatrib; Patrin. O6-(4-bromothenyl)guanine; 6-(4-Bromothenyloxy)-7H-purin-2-amine.

More details are to be found here

Smile code:
NC1=NC(OCC2=CC(Br)=CS2)=C3N=CNC3=N1
MDL Number:
MFCD23703756
Purity :
98%
Available in stock:
10.226 g

Smile code:
NC1=NC(OCC2=CC(Br)=CS2)=C3N=CNC3=N1
MDL Number:
MFCD23703756
Purity :
98%
Available in stock:
10.226 g

Smile code:
NC1=NC(OCC2=CC(Br)=CS2)=C3N=CNC3=N1
MDL Number:
MFCD23703756
Purity :
98%
Available in stock:
10.226 g