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Suppliers for

Jervine



Properties

CAS   469-59-0 
Formula   C27H39NO3 
EINECS   207-417-9 

Structure

8 Registered suppliers


Molecular Formula: C27H39NO3
Molecular Weight: 425.6
Hazard Symbols: Xn
UN Number: UN 2811 6.1/PG 3
WGKGermany: 3
PackingGroup: III
HS Code: 29349990

Description :
Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog(Shh) signaling. It is an inhibitor of Smo and derived from the Veratrum plant species. Jervine can be used to induce abnormal morphogenesis in a number of experimental models.
  • Molecular Weight :425.60
  • Boiling Point :592.0±50.0°C at 760 mmHg
  • Melting Point :243.5-244.5°C
  • Purity :> 98%
Molecular Formula :
C27H39NO3
Canonical SMILES :
CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)O)C)NC1
InChI :
InChI=1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2,1-4H3/t14-,16+,18-,19-,20-,21+,23+,24-,26-,27-/m0/s1
InChIKey :
CLEXYFLHGFJONT-DNMILWOZSA-N
Solubility :
Soluble in Chloroform (Slightly), Ethanol (Slightly)
Appearance :
White to Beige Solid
Application :
Antibacterial
Storage : Store at -20°C
Synonyms :
Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one, 2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-, (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-; (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-Hexadecahydro-3-hydroxy-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one; Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3β,23β)-; Jervin; NSC 23898; NSC 7520; Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one, 2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-, [3S-(3α,6aα,6bβ,9α(3'S*,3'aR*,6'R*,7'aS*),11aβ,11bα)]-

More details are to be found here
Description :
Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog(Shh) signaling. It is an inhibitor of Smo and derived from the Veratrum plant species. Jervine can be used to induce abnormal morphogenesis in a number of experimental models.
  • Molecular Weight :425.60
  • Boiling Point :592.0±50.0°C at 760 mmHg
  • Melting Point :243.5-244.5°C
  • Purity :> 98%
Molecular Formula :
C27H39NO3
Canonical SMILES :
CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)O)C)NC1
InChI :
InChI=1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2,1-4H3/t14-,16+,18-,19-,20-,21+,23+,24-,26-,27-/m0/s1
InChIKey :
CLEXYFLHGFJONT-DNMILWOZSA-N
Solubility :
Soluble in Chloroform (Slightly), Ethanol (Slightly)
Appearance :
White to Beige Solid
Application :
Antibacterial
Storage : Store at -20°C
Synonyms :
Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one, 2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-, (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-; (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-Hexadecahydro-3-hydroxy-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one; Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3β,23β)-; Jervin; NSC 23898; NSC 7520; Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one, 2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-, [3S-(3α,6aα,6bβ,9α(3'S*,3'aR*,6'R*,7'aS*),11aβ,11bα)]-

More details are to be found here
Description :
Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog(Shh) signaling. It is an inhibitor of Smo and derived from the Veratrum plant species. Jervine can be used to induce abnormal morphogenesis in a number of experimental models.
  • Molecular Weight :425.60
  • Boiling Point :592.0±50.0°C at 760 mmHg
  • Melting Point :243.5-244.5°C
  • Purity :> 98%
Molecular Formula :
C27H39NO3
Canonical SMILES :
CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)O)C)NC1
InChI :
InChI=1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2,1-4H3/t14-,16+,18-,19-,20-,21+,23+,24-,26-,27-/m0/s1
InChIKey :
CLEXYFLHGFJONT-DNMILWOZSA-N
Solubility :
Soluble in Chloroform (Slightly), Ethanol (Slightly)
Appearance :
White to Beige Solid
Application :
Antibacterial
Storage : Store at -20°C
Synonyms :
Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one, 2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-, (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-; (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-Hexadecahydro-3-hydroxy-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one; Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3β,23β)-; Jervin; NSC 23898; NSC 7520; Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one, 2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-, [3S-(3α,6aα,6bβ,9α(3'S*,3'aR*,6'R*,7'aS*),11aβ,11bα)]-

More details are to be found here
Description :
Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog(Shh) signaling. It is an inhibitor of Smo and derived from the Veratrum plant species. Jervine can be used to induce abnormal morphogenesis in a number of experimental models.
  • Molecular Weight :425.60
  • Boiling Point :592.0±50.0°C at 760 mmHg
  • Melting Point :243.5-244.5°C
  • Purity :> 98%
Molecular Formula :
C27H39NO3
Canonical SMILES :
CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)O)C)NC1
InChI :
InChI=1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2,1-4H3/t14-,16+,18-,19-,20-,21+,23+,24-,26-,27-/m0/s1
InChIKey :
CLEXYFLHGFJONT-DNMILWOZSA-N
Solubility :
Soluble in Chloroform (Slightly), Ethanol (Slightly)
Appearance :
White to Beige Solid
Application :
Antibacterial
Storage : Store at -20°C
Synonyms :
Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one, 2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-, (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-; (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-Hexadecahydro-3-hydroxy-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one; Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3β,23β)-; Jervin; NSC 23898; NSC 7520; Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one, 2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-, [3S-(3α,6aα,6bβ,9α(3'S*,3'aR*,6'R*,7'aS*),11aβ,11bα)]-

More details are to be found here

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Properties:

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